… -inspired scaffold diversity was investigated by the generation of 11 novel scaffolds. The
significance of this work includes (1) providing an in-depth understanding of the scaffold SAR of …

… To assess the scaffold diversity, we classified them into ten chemical classes,
aminopyrimidines, fused aminopyrimidines, aminopyrazoles, aminothiazoles, aminotriazines/…

… and diversity: The synthesis of compound libraries with a high degree of scaffold diversity …
using natural products as a source of scaffold diversity. In this Minireview, recent developments …

… the natural-product-inspired scaffolds continue to be rich sources for … scaffold defines the
characteristic structural core of a large family of oxindole alkaloids with pronounced and diverse …

… The indole scaffold is one of the most widespread heterocycles in the naturally occurring
and synthetic bioactive compounds including anticancer agents. Due to its biodiversity and …

… , new protein-based scaffolds have been designed and … These entities can be placed into
two categories: scaffolds … armadillo repeat protein-based scaffolds are members of the second …

… have been approved to be as anti-tumor agents in clinic. For instance, … with diverse structures
have been developed in recent decades. Furthermore, indole ring is an important scaffold …

… scaffolds has also been evidenced through number of research article and patent
literature. The pyrimidines based scaffolds … their potential to interact with diverse enzymes/targets/…

… a negative attribute for antitumor agents because the goal was … antibacterial activity in an
antitumor agent should be ignored [… agents within the same scaffold series may display diversity …

… with scaffold diversity and successfully identified a novel spiropyrazolone antitumor scaffold.
… , which represents a good starting point for the development of novel antitumor agents. …