… DNA sequence, is generating increasing interest as a means to help clarify disease pathogenesis
and outcomes. Although genome… cholangitis (PBC) and primary sclerosing cholangitis …

… DNA sequencing. Liver biopsies were obtained from patients with primary sclerosing cholangitis
(… Samples from patients with primary biliary cirrhosis and primary sclerosing cholangitis (…

Background Primary sclerosing cholangitis (PSC) is a well‐described risk factor for the
development of cholangiocarcinoma (CCA). Early detection of CCA in these patients is of great …

… Whole genome sequencing (WGS) can provide additional knowledge of mutational spectra
… sequencing. We describe the molecular landscape of CCA using whole-genome sequencing …

… A limited number of genetic risk factors have been reported in primary sclerosing cholangitis
(PSC… of bile microbial community composition in 39 PSC patients by 16S rRNA sequencing. …

… BaCKgRoUND aND aIMS: Lifetime risk of biliary tract cancer (BTC) in primary sclerosing
cholangitis (… We performed tumor DNA sequencing at 42 clinically relevant genetic loci to detect …

… Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of the bile ducts …
1 a) using classical Sanger sequencing. A total of 29 SNPs were detected, of which 22 were …

… Clinical presentations reflect the underlying sequence of bile duct injury and fibrosis leading
to stricturing, cholestasis, and biliary cirrhosis with progressive liver dysfunction. Primary …

… We aimed to characterize the genetic susceptibility to primary sclerosing cholangitis (PSC)
by means of a genome-wide association analysis of single nucleotide polymorphism (SNP) …

Objective Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease often
leading to end-stage liver disease. Its pathogenesis remains largely unknown, although …