Evaluation of the role of MHC class II alleles, haplotypes and selected amino acid sequences in primary sclerosing cholangitis

PT Donaldson, S Norris - Autoimmunity, 2002 - Taylor & Francis
… The first-domain amino acid sequences of the HLA DRb-, DQa-and DQb-polypeptides
were determined from the published allele-DNA sequences[31] for all patients and controls. …

… of brush cytology samples improves the detection of high-grade dysplasia and cholangiocarcinoma in patients with primary sclerosing cholangitis: A retrospective and …

S Boyd, T Mustamäki, N Sjöblom, A Nordin… - Hepatology …, 2024 - journals.lww.com
… By using next-generation sequencing (NGS), we … that occur during primary sclerosing
cholangitis carcinogenesis. BC … Among the 75 patients, sufficient DNA amount or sequencing

The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease

J Torres, C Palmela, H Brito, X Bao… - United European …, 2018 - journals.sagepub.com
… × 300 pair-end sequencing at high depth. The paired sequence readings were merged and
… ) using paired-end assembler for DNA sequences (PANDAseq). The processed readings …

DOP80 Multi-omic sequencing reveals distinctive gene expression and DNA methylation alterations as potential predictors of primary sclerosing cholangitis …

O Lawal, A Rodriguez-Sosa… - Journal of Crohn's …, 2023 - academic.oup.com
… Background: Primary sclerosing cholangitis (PSC) is a … methyl-capture sequencing and mRNA
sequencing to colonic … distinct gene expression and DNA methylation alterations that differ…

[HTML][HTML] Characterization of cultured cholangiocytes isolated from livers of patients with primary sclerosing cholangitis

JH Tabibian, CE Trussoni, SP O'hara, PL Splinter… - Laboratory …, 2014 - Elsevier
… FASTQ sequence reads were aligned to both the latest available human genome (19) and
… of exon junction database for the sequencing length of 50 bases were generated using exon …

Biallelic mutations in DCDC2 cause neonatal sclerosing cholangitis in a Chinese family

Y Lin, J Zhang, X Li, D Zheng, X Yu, Y Liu, F Lan… - Clinics and Research in …, 2020 - Elsevier
… neonatal sclerosing cholangitis (NSC… sequencing (WES) was performed to find the possible
disease-causing mutations of this family. The mutation was confirmed by Sanger sequencing

[HTML][HTML] Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis

L Bajer, M Kverka, M Kostovcik, P Macinga… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To characterize the gut bacterial microbiota of patients with primary sclerosing cholangitis
(PSC) and ulcerative colitis (UC). METHODS Stool samples were collected and relevant …

[HTML][HTML] Altered gut microbial metabolism of essential nutrients in primary sclerosing cholangitis

M Kummen, LB Thingholm, MC Rühlemann, K Holm… - Gastroenterology, 2021 - Elsevier
… when using 16S ribosomal RNA gene sequencing. Furthermore, one important possibility
is … sequencing. The aim of our study was to apply large-scale metagenomic sequencing in 2 …

[PDF][PDF] Low-frequency and rare DNA sequence variants associated with primary sclerosing cholangitis susceptibility

R Alberts, MC Visschedijk, S Mucha… - New genes, rare …, 2018 - research.rug.nl
… Primary sclerosing cholangitis (PSC) is a rare, progressive … Several genome wide association
studies have found over … results were validated using Sanger sequencing on the same …

Primary sclerosing cholangitis in two brothers: report of a family with special emphasis on molecular HLA and MICA genotyping

W Van Steenbergen, E De Goede… - European journal of …, 2005 - journals.lww.com
… Immune mechanisms play a role in the pathogenesis of primary sclerosing cholangitis (PSC), …
Sequences were electrophoresed on an ABI 377 DNA sequencer and analysed using the …