… Clearly, scorpion toxins have played important, crucial roles in determining potassium
channel structure and function. In this review, we will discuss how work with scorpion venom …

… state with remarkable effects on toxin binding. In this … of potassium channels explored using
scorpion toxin tools and discuss future work in the field of scorpion toxin-potassium channel …

… Kv1.2, than on Kv1.1 and Kv1.3 potassium channels. However, we can speculate that the
specificity of scorpion toxins is driven by the overall distribution of ionisable side chains. This …

… ion-channels, responsible for either sodium, potassium, … of scorpion toxins specific for
potassium channels, and on their structure–activity relationships. The overall fold of all these toxins …

… venom: out of ∼400 polypeptide ligands found in UniProt, 250 are scorpion toxins ( 12 ).
All known scorpion toxins affecting potassium channels (KTx) are peptides that act as channel …

… potassium channels. CIur results indicatethatthis region isprobablytheonlypartoftheion channel
that directly contacts bound scorpion toxins. … toxin-sensitive to a tolxin-insensitive channel …

… ) and eukaryotic Kv channels, we explored possibilities of transferring the scorpion toxin
receptor site of human (h)Kv1.3 channels to the toxin-insensitive KcsA channels. Accordingly, …

… K + channel toxins, … of scorpion toxins. The pairing of its disulfide bridges, deduced from
MS of trypsin-digested peptide, is similar to that of classical four disulfide bridged scorpion toxins …

… Scorpion toxins affecting K + channels (KTxs) represent important pharmacological tools …
Here, we report molecular characterization of seven new KTxs in the scorpion Mesobuthus …

… , from venom of the scorpion Mesobuthus eupeus. MeuTx3B … large conductance
calcium-activated potassium channels (BK), … inhibits human voltage-gated potassium channel …