… of lead molecules in drug discovery. Refinements and … screening methods, concomitant
developments in cheminformatics including identification, design and manipulation of drug…

… screening (HTS) technologies offered great promise for accelerating the drug discovery
process by enabling huge libraries of compounds to be synthesized and screened in short …

… Since drug absorption potential has become a more important … drug development early
in the drug discovery process, there is a need for reliable screening methods to assess drug …

… also a direction to the drug discovery teams (what will not … discovery toxicology screening
strategy which focuses on: (i) serious adverse drug reactions that most frequently impact drug …

… Using a docking-based virtual screening strategy in conjunction with chemical synthesis …
By applying a docking-based virtual screening strategy that targets the binding pocket of CypA, …

… Abstract: The discovery of bioactive molecules is an … new strategies are continuously
searched for in order to optimize this process. Virtual Screening (VS) is one of the recent strategies …

… situations and apply strategies in whichstereochemical/ regiochemical … drug-discovery
screening and drug-developmentoptimization. When complete, the combinatorial drug-discovery …

… , screening libraries and screening strategies. The ‘genomics‘ approach was replaced by a
diverse array of discovery strategies, … new microbial sources, screening for synthetic inhibitors …

… Indeed, there are now a number of drugs whose development was heavily influenced by or
based on structure-based design and screening strategies, such as HIV protease inhibitors. …

… Long after the advent of acetylsalicylic acid and penicillin, as the golden age of drug discovery
started … Experimental high-throughput screening (HTS) and combinatorial chemistry were …