Enhancement of flavone levels through overexpression of chalcone isomerase in hairy root cultures of Scutellaria baicalensis

NI Park, H Xu, X Li, SJ Kim, SU Park - Functional & integrative genomics, 2011 - Springer
… A complementary DNA (cDNA) encoding Scutellaria baicalensis chalcone isomerase (SbCHI)
was isolated using rapid amplification of cDNA ends polymerase chain reaction. After the …

Specific Flavonoids and Their Biosynthetic Pathway in Scutellaria baicalensis

T Pei, M Yan, Y Huang, Y Wei, C Martin… - Frontiers in plant …, 2022 - frontiersin.org
… with three molecules of malonyl CoA by a specific isoform of chalcone synthase (CHS-2),
and isomerized by chalcone isomerase (CHI) to form pinocembrin, a flavanone without a 4′-…

Comparative Genome Analysis of Scutellaria Baicalensis and Scutellaria Barbata Reveals the Evolution of Active Flavonoid Biosynthesis

Z Xu, R Gao, X Pu, R Xu, J Wang… - Genomics …, 2020 - academic.oup.com
… The biosynthetic genes involved in the synthesis of Scutellaria specific flavones and
glycosides, containing genes encoding chalcone synthase, chalcone isomerase, CYP450s, O-…

A specialized flavone biosynthetic pathway has evolved in the medicinal plant, Scutellaria baicalensis

Q Zhao, Y Zhang, G Wang, L Hill, JK Weng… - Science …, 2016 - science.org
… a CoA ligase, which is then condensed with malonyl-CoA by chalcone synthase (CHS) to
form a chalcone, and then isomerized by chalcone isomerase (CHI) to form pinocembrin, a 4′-…

A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of Scutellaria baicalensis

ZL Wang, S Wang, Y Kuang, ZM Hu, X Qiao… - Pharmaceutical …, 2018 - Taylor & Francis
Context: Scutellaria baicalensis Georgi (Lamiaceae) is a popular medicinal plant. Its roots
are used as the famous traditional Chinese medicine Huang-Qin, which is recorded in …

Expression of the chalcone synthase gene in Scutellaria baicalensis hairy root cultures was unusually reduced by environmental stresses

Y Zhou, S Nagashima, M Hirotani, H SUZUKI… - Plant …, 2003 - jstage.jst.go.jp
… isolated frorn a CDNA Iibrary derived from hairy root culturcs of Scutellaria baicalensis
Georgi by sc~eening with a I.4 kbp full length CIIS cDNA of Pha,s'.eolus vulgaris as the probe. …

Scutellaria baicalensis, the golden herb from the garden of Chinese medicinal plants

Q Zhao, XY Chen, C Martin - Science bulletin, 2016 - Springer
… with malonyl CoA by a specialised isoform of chalcone synthase (SbCHS-2) to form a
chalcone, which is then isomerized by the same chalcone isomerase (CHI) that acts in scutellarin …

Deep Sequencing of the Scutellaria baicalensis Georgi Transcriptome Reveals Flavonoid Biosynthetic Profiling and Organ-Specific Gene Expression

J Liu, J Hou, C Jiang, G Li, H Lu, F Meng, L Shi - PLoS One, 2015 - journals.plos.org
… And 12 of them have been discovered in this study: chalcone synthase (K00660, CHS);
chalcone isomerase … Except chalcone isomerase and coumaroylquinate (coumaroylshikimate) 3'-…

Whole genome and transcriptome reveal flavone accumulation in Scutellaria baicalensis roots

S Hu, D Wang, W Wang, C Zhang, Y Li… - Frontiers in Plant …, 2022 - frontiersin.org
… the chalcone synthase (CHS) and chalcone isomerase (CHI) conversion of naringenin chalcone
… coenzyme A are converted to pine chalcone by chalcone synthase (CHS) and chalcone

[PDF][PDF] CHS and UBGAT expression and baicalin accumulation in the roots of Scutellaria baicalensis Georgi during cultivation seasons

W WANG, J CHEN, T ZHOU - 复旦学报(自然科学版), 2006 - tiandz.com
… the expression levels of CHS (chalcone sy nthase)and UBGAT … in the roots of Scutellaria
baicalensis Georgi during cultivation … CHS , chalcone synthase;CHI , chalcone isomerase;FNS , …