First-and second-line drugs and drug resistance

HN Jnawali, S Ryoo - Tuberculosis-current issues in diagnosis …, 2013 - books.google.com
… of multidrug resistant TB (MDR-TB), ie which is resistant to at … it requires the use of second-line
drugs that are difficult to … treatment of drug susceptible or single drug resistant TB is an …

Evaluation of the MTBDRsl Test for Detection of Second-Line-Drug Resistance in Mycobacterium tuberculosis

VS Kiet, NTN Lan, DD An, NH Dung… - Journal of clinical …, 2010 - Am Soc Microbiol
… ” resistance to second-line drugs, but it is an accurate rapid screening test for the identification
of second-line drug resistance, … Detection of ethambutol (64.2%) resistance in Vietnamese …

Molecular detection of mutations associated with first-and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium …

PJ Campbell, GP Morlock, RD Sikes… - Antimicrobial agents …, 2011 - Am Soc Microbiol
… associated with drug resistance to rapidly and accurately determine the drug susceptibility
… study were not associated with drug resistance. Each resistance-associated locus examined …

Multidrug-resistant tuberculosis treatment outcomes in relation to treatment and initial versus acquired second-line drug resistance

JP Cegielski, E Kurbatova… - Clinical Infectious …, 2016 - academic.oup.com
… Patients with MDR tuberculosis starting second-line drug treatment were enrolled in a …
) initial and acquired resistance to fluoroquinolones and second-line injectable drugs (SLIs) …

Detection of first-and second-line drug resistance in Mycobacterium tuberculosis clinical isolates by pyrosequencing

A Engström, N Morcillo, B Imperiale… - Journal of clinical …, 2012 - Am Soc Microbiol
… that the method failed to detect drug resistance in the case where an isolate had mutations
in codons 505 and 511. Eleven phenotypically RIF-resistant isolates in this study did not …

Emergence of HIV drug resistance during first-and second-line antiretroviral therapy in resource-limited settings

MC Hosseinipour, RK Gupta, G Van Zyl… - The Journal of …, 2013 - academic.oup.com
… Collaborative HIV and Drug Resistance Network workshop in … the emergence of first-line drug
resistance mutations after 12 … to second-line therapy and summarize HIV resistance among …

… patients with multidrug-resistant and extensively drug-resistant tuberculosis according to drug susceptibility testing to first-and second-line drugs: an individual patient …

ML Bastos, H Hussain, K Weyer… - Clinical infectious …, 2014 - academic.oup.com
drug susceptibility testing (DST) for pyrazinamide, ethambutol, and second-line tuberculosis
drugs… pyrazinamide, ethambutol, and second-line drugs with treatment outcomes in patients …

First-and second-line drug resistance patterns among previously treated tuberculosis patients in India

CN Paramasivan, F Rehman, F Wares… - … of tuberculosis and …, 2010 - ingentaconnect.com
resistance to any fluoroquinolone and at least one of the three injectable secondline drugs
(SLDs)—… To date, limited representative drug resistance data are available from India, with no …

Rapid genomic first-and second-line drug resistance prediction from clinical Mycobacterium tuberculosis specimens using Deeplex-MycTB

S Feuerriegel, TA Kohl, C Utpatel… - European …, 2021 - Eur Respiratory Soc
… of resistance and susceptibility by Deeplex-MycTB and pDST data for the first-line drugs
obtained after … However, data included mainly mutations conferring resistance to first-line drugs. …

Comparative Study on Genotypic and Phenotypic Second-Line Drug Resistance Testing of Mycobacterium tuberculosis Complex Isolates

J van Ingen, S Simons, R de Zwaan… - Journal of clinical …, 2010 - Am Soc Microbiol
resistance to capreomycin and the aminoglycosides (2-5). … for resistance to several second-
and third-line drugs, … dilution method has been used for second-line DST for 2 decades (18). …