Erlotinib, cabozantinib, or erlotinib plus cabozantinib as second-line or third-line treatment of patients with EGFR wild-type advanced non-small-cell lung cancer …

JW Neal, SE Dahlberg, HA Wakelee, SC Aisner… - The lancet …, 2016 - thelancet.com
patients to erlotinib treatment, 40 patients to cabozantinib treatment, and 43 patients to erlotinib
… (erlotinib [n=38], cabozantinib [n=38], erlotinib plus cabozantinib [n=35]). Compared with …

Efficacy and safety of erlotinib versus chemotherapy in second-line treatment of patients with advanced, non-small-cell lung cancer with poor prognosis (TITAN): a …

T Ciuleanu, L Stelmakh, S Cicenas, S Miliauskas… - The lancet …, 2012 - thelancet.com
Erlotinib, docetaxel, and pemetrexed are approved for the second-line treatment of non-small-…
tolerability of second-line erlotinib versus chemotherapy in patients with refractory NSCLC. …

Second-line erlotinib in patients with advanced non-small-cell lung cancer: subgroup analyses from the TRUST study

DF Heigener, YL Wu, N van Zandwijk, P Mali… - Lung Cancer, 2011 - Elsevier
… in patients receiving second-line erlotinib confirm that oral dosing with erlotinib offers patients
a … efficacy and reduced toxicity compared with conventional second-line chemotherapy. …

[HTML][HTML] Erlotinib as second-line treatment in patients with advanced non-small-cell lung cancer and asymptomatic brain metastases: a phase II study (CTONG–0803)

YL Wu, C Zhou, Y Cheng, S Lu, GY Chen, C Huang… - Annals of …, 2013 - Elsevier
… evaluate the efficacy and safety of erlotinib as second-line therapy in NSCLC patients with
BM. … As erlotinib is approved for all patients regardless of EGFR mutation status in second line, …

[PDF][PDF] Second-line treatment of advanced NSCLC: Comparison of efficacy of erlotinib and chemotherapy

O Fiala, M Pesek, J Finek, J Krejci, Z Bortlicek… - Neoplasma, 2013 - researchgate.net
… Total number of patients was 290. A group treated with chemotherapy … second line consisted
of 150 patients and a group treated with erlotinib in the second line consisted of 140 patients

Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised …

MC Garassino, O Martelli, M Broggini, G Farina… - The lancet …, 2013 - thelancet.com
… Our results show that chemotherapy is more effective than erlotinib for second-line
treatment for previously treated patients with NSCLC who have wild-type EGFR tumours. …

A phase II trial of erlotinib monotherapy in advanced pancreatic cancer as a first-or second-line agent

C Fountzilas, R Chhatrala, N Khushalani, W Tan… - Cancer chemotherapy …, 2017 - Springer
… In this phase II trial we sought to evaluate the efficacy of erlotinib monotherapy in patients
with APC who had disease refractory to or ineligibility for gemcitabine-based therapy. …

Retrospective practice review of treatment of metastatic non-small-cell lung cancer with second-line erlotinib

B Melosky, J Agulnik, H Assi - Current Oncology, 2008 - mdpi.com
… The small size and retrospective nature of this case series limits the findings of this analysis
of secondline erlotinib in NSCLC patients. In 50% of cases, investigators cited clinical …

A randomized phase 2 trial of erlotinib versus pemetrexed as secondline therapy in the treatment of patients with advanced EGFR wild‐type and EGFR FISH‐positive …

N Li, W Ou, H Yang, QW Liu, SL Zhang, BX Wang… - Cancer, 2014 - Wiley Online Library
… , erlotinib was effective in patients with wild-… erlotinib arms (P = .02).23 In a recent phase
3 trial, a comparison of docetaxel with erlotinib as second-line or third-line treatment in patients

A randomized, double-blind, phase III study comparing two doses of erlotinib for second-line treatment of current smokers with advanced non-small-cell lung cancer …

EF Smit, YL Wu, R Gervais, C Zhou, E Felip, J Feng… - Lung Cancer, 2016 - Elsevier
erlotinib metabolism versus non-smoking patients, which reduces exposure. Therefore, an
increased erlotinib … and safety of 300 mg erlotinib (E300) as second-line therapy in current …