Cost–effectiveness of afatinib and erlotinib as second-line treatments for advanced squamous cell carcinoma of the lung

J Zhu, W He, M Ye, J Fu, YB Chu, YY Zhao… - Future …, 2018 - Taylor & Francis
… The indication of afatinib and erlotinib for SqCC of the lung had not been approved.
However, because the oncologist and patients would still pursue these agents as second-line

First-line erlotinib therapy until and beyond response evaluation criteria in solid tumors progression in Asian patients with epidermal growth factor receptor mutation …

K Park, CJ Yu, SW Kim, MC Lin, V Sriuranpong… - JAMA …, 2016 - jamanetwork.com
erlotinib therapy may be most beneficial in patients with good response to first-line erlotinib,
… In brief, it is conceivable that patients with slow PD could benefit from continuation of EGFR …

Predictive value of a proteomic signature in patients with non-small-cell lung cancer treated with second-line erlotinib or chemotherapy (PROSE): a biomarker …

V Gregorc, S Novello, C Lazzari, S Barni… - The lancet …, 2014 - thelancet.com
… in the comparison of erlotinib and chemotherapy in patients with non-small-cell lung cancer.
… survival for erlotinib versus chemotherapy in the second-line setting. Patients classified as …

… and secondary epidermal growth factor receptor (EGFR) T790M mutation among first‐line gefitinib, erlotinib and afatinib‐treated non‐small cell lung cancer patients …

YT Lin, JS Chen, WY Liao, CC Ho… - … Journal of Cancer, 2019 - Wiley Online Library
… Our study retrospectively enrolled patients who had received gefitinib, erlotinib or afatinib
for first-line treatment of stage IV or post-operative recurrent (advanced) NSCLC between 2014/…

[HTML][HTML] Cost-effectiveness of first-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy

I Khan, S Morris, A Hackshaw, SM Lee - BMJ open, 2015 - bmjopen.bmj.com
… ,2 the potential economic impact of erlotinib use in the 60% of treated patients who develop
rash is … of erlotinib versus placebo overall and within a predefined subgroup of patients who …

Erlotinib as second‑or third‑line treatment in elderly patients with advanced non‑small cell lung cancer: Keio Lung Oncology Group Study 001 (KLOG001)

M Miyawaki, K Naoki, S Yoda… - Molecular and …, 2017 - spandidos-publications.com
… phase II trial of second- or third-line erlotinib treatment in elderly patients with NSCLC. The
primary endpoint was overall response rate (ORR) and the secondary endpoints were PFS, …

A randomized, double-blind, phase III study comparing two doses of erlotinib for second-line treatment of current smokers with advanced non-small-cell lung cancer …

EF Smit, YL Wu, R Gervais, C Zhou, E Felip, J Feng… - Lung Cancer, 2016 - Elsevier
erlotinib metabolism versus non-smoking patients, which reduces exposure. Therefore, an
increased erlotinib … and safety of 300 mg erlotinib (E300) as second-line therapy in current …

Erlotinib in first-line therapy for non-small cell lung cancer: a prospective phase II study

DR Choi, DH Lee, CM Choi, SW Kim, C Suh… - Anticancer …, 2011 - ar.iiarjournals.org
… , some patient's performance status improved noticeably and rapidly after erlotinib therapy.
… the use of first-line erlotinib therapy, even in patients having favorable molecular predictors …

… for Treatment and Study Design of TAILOR: A Randomized Phase III Trial of Second-line Erlotinib Versus Docetaxel in the Treatment of Patients Affected by Advanced …

G Farina, F Longo, O Martelli, I Pavese, A Mancuso… - Clinical Lung Cancer, 2011 - Elsevier
patients benefit from EGFR tyrosine kinase inhibitors, such as gefitinib and erlotinib, whereas
their role in the treatment of patients … to optimize second-line treatment in NSCLC patients

[HTML][HTML] Final overall survival results from a randomised, phase III study of erlotinib versus chemotherapy as first-line treatment of EGFR mutation-positive advanced …

C Zhou, YL Wu, G Chen, J Feng, XQ Liu, C Wang… - Annals of …, 2015 - Elsevier
… In the current study, ∼40% of erlotinib-treated patients in the overall population and exon
19 deletion subpopulation did not receive any post-study treatment. On the other hand, almost …