Mechanisms of secondary brain injury

BK Siesjö, P Siesjö - European journal of anaesthesiology, 1996 - cambridge.org
Secondary brain damage can be defined as cell injury which is not obviously present …
secondary damage. The results illustrate the facts that the the concept of secondary brain injury

Secondary brain injury: predicting and preventing insults

C Lazaridis, CG Rusin, CS Robertson - Neuropharmacology, 2019 - Elsevier
… patients after severe traumatic brain injury (TBI). Adherence to the brain trauma foundation
… towards intracranial hypertension and secondary brain injury have come under scrutiny after …

The role of secondary brain injury in determining outcome from severe head injury

RM Chesnut, LF Marshall, MR Klauber… - 50 Landmark …, 2019 - api.taylorfrancis.com
… of physiologic factors in the development of secondary brain injury. From the Traumatic
Coma Data bank, 717 patients with severe trauma brain injury (GCS < 9) were analyzed and …

Primary and secondary brain injury

AD Mendelow, PJ Crawford - Head injury, 1997 - api.taylorfrancis.com
… By contrast, secondary brain damage occurs at some time … brain damage, then to prevent
and treat secondary brain damage. Recent research has shown that, although primary brain

Molecular pathophysiology of cerebral hemorrhage: secondary brain injury

J Aronowski, X Zhao - Stroke, 2011 - Am Heart Assoc
… within brain parenchyma triggers a series of adverse events causing secondary insults and
… This article discusses selected aspects of secondary brain injury after ICH and outlines key …

[图书][B] Intracranial hemorrhage: mechanisms of secondary brain injury

J Lok, W Leung, S Murphy, W Butler, N Noviski, EH Lo - 2011 - Springer
… Intracerebral hemorrhage initiates many cellular responses beyond those that restore
hemostasis, and these responses may contribute to secondary brain injury (see Fig. 1). ICH is …

Clinical evidence of inflammation driving secondary brain injury: a systematic review

HE Hinson, S Rowell, M Schreiber - Journal of Trauma and Acute …, 2015 - journals.lww.com
… humans that inflammation is linked to secondary brain injury?” As the experimental evidence
… focus on the clinical evidence for inflammation as a mechanism of secondary brain injury. …

Promising strategies to minimize secondary brain injury after head trauma

H Bayr, RSB Clark, PM Kochanek - Critical care medicine, 2003 - journals.lww.com
… currently in clinical trials for severe traumatic brain injury: a) the novel pharmacologic agent
… a successful approach to severe traumatic brain injury. Traumatic brain injury (TBI) is a major …

Clinical considerations in the reduction of secondary brain injury

CE Doberstein, DA Hovda, DP Becker - Annals of emergency medicine, 1993 - Elsevier
… that can cause secondary brain injury. Recovery after traumatic brain injury is related to
both the severity of the initial mechanical trauma and the presence of secondary insults. By …

A review of traumatic brain injury and the gut microbiome: insights into novel mechanisms of secondary brain injury and promising targets for neuroprotection

CS Zhu, R Grandhi, TT Patterson, SE Nicholson - Brain sciences, 2018 - mdpi.com
injury, leading to a pro-inflammatory state within the central nervous system (CNS). Herein,
we examine traumatic brain injury (… clinical outcomes and preventing secondary brain injury. …