… for the isolation of insulin secretory granules from a transplantable rat islet cell tumour. These
… approximately 1 mg of granule protein. The isolated granules were essentially free of other …

… impossible to obtain a pure beta secretory granule fraction, this study was directed … rat islets,
with the adenine nucleotide and insulin composition of the secretory granule fraction of islets…

… In the present paper, a method is described for the isolation of a secretory granule fraction
from rat islets of Langerhans by the use of differential and density-gradient centrifugation ; …

… rat islets at the level of individual secretory granules. Elemental analysis of thin, dried
cryosections showed that beta granules … granules contained elevated P and Mg. Although a single …

… Secretory granule-enriched fractions prepared from isolated rat islets of Langerhans, previously
… and immunoreactive rat insulins I and II were recovered in the insoluble granule core …

… secretory granule fraction, isolated from rat islets of Langerhans by differential centrifugation,
was used for investigating the stability of the beta granules during … ; the granules possessed …

… protein in the regenerating islets of the rats at two weeks and … mal rat islets or in the islets
of the rats one year after the pan… central granular core of the regenerating Beta cell secretory …

… Lysosomal degradation of entire secretory granules by crinophagy constitute another …
secretory granule proteins are also observed between tumour tissue and normal rat islets [14, 171. …

… Beta granules isolated from rat islets of Langerhans and subjected only to phosphotungstic
… of beta granules in intact cells . In shadowed preparations, the granules were spherical in …

… impure secretion granule fraction prepared from rat islets of … is similar to that observed in
whole islets, while externally … insulin we have prelabeled rat crude secretion granules with [3H]…