[HTML][HTML] Cellular senescence and the senescence-associated secretory phenotype as drivers of skin photoaging
E Fitsiou, T Pulido, J Campisi, F Alimirah… - Journal of Investigative …, 2021 - Elsevier
… Because the senescent phenotype is variable and depends on the cell type and the … senesce
after UV and the cell-specific mechanisms they use to maintain the senescent phenotype, …
after UV and the cell-specific mechanisms they use to maintain the senescent phenotype, …
The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration
B Ritschka, M Storer, A Mas, F Heinzmann… - Genes & …, 2017 - genesdev.cshlp.org
… analysis on primary mouse keratinocytes undergoing oncogene-induced senescence (OIS) …
As expected, senescent keratinocytes exhibited hallmark features of senescence, including …
As expected, senescent keratinocytes exhibited hallmark features of senescence, including …
[HTML][HTML] Insights into epithelial cell senescence from transcriptome and secretome analysis of human oral keratinocytes
RE Schwartz, MN Shokhirev, LR Andrade… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
… senescence associated secretory phenotype, including HSP60, which localizes to the surface
of EVs. Finally, EVs from senescent … Our results highlight senescence changes in epithelial …
of EVs. Finally, EVs from senescent … Our results highlight senescence changes in epithelial …
[HTML][HTML] The senescence-associated secretory phenotype: critical effector in skin cancer and aging
K Ghosh, BC Capell - Journal of Investigative Dermatology, 2016 - Elsevier
… Although keratinocytes and melanocytes have typically displayed similar responses and
comparable results when subjected to identical experimental conditions, this caveat must be …
comparable results when subjected to identical experimental conditions, this caveat must be …
The role of icIL-1RA in keratinocyte senescence and development of the senescence-associated secretory phenotype
SE Niklander, HL Crane, L Darda… - Journal of cell …, 2021 - journals.biologists.com
… evidence that senescent cells, through the senescence-associated secretory phenotype (…
, but the control of its activity in the senescence programme has not been elucidated. IL-1 …
, but the control of its activity in the senescence programme has not been elucidated. IL-1 …
Cell aging and cellular senescence in skin aging—Recent advances in fibroblast and keratinocyte biology
F Gruber, C Kremslehner, L Eckhart… - Experimental gerontology, 2020 - Elsevier
… on cell-specific aging and senescent phenotypes of fibroblasts and keratinocytes and the
impact … oxidation, telomere shortening, a secretory phenotype and survival within the tissue) of …
impact … oxidation, telomere shortening, a secretory phenotype and survival within the tissue) of …
Autophagy deficient melanocytes display a senescence associated secretory phenotype that includes oxidized lipid mediators
C Ni, MS Narzt, IM Nagelreiter, CF Zhang… - The international journal …, 2016 - Elsevier
… into keratinocytes. We have previously shown that mice whose melanocytes or keratinocytes
… In cell culture the Atg7 deficient melanocytes were prone to premature senescence and …
… In cell culture the Atg7 deficient melanocytes were prone to premature senescence and …
The senescence-associated secretory phenotype: Fueling a wound that never heals
T Pulido, MC Velarde, F Alimirah - Mechanisms of Ageing and …, 2021 - Elsevier
… how cellular senescence and the senescence-associated secretory phenotype (SASP) …
In order to better distinguish between senescent cell populations that are beneficial versus …
In order to better distinguish between senescent cell populations that are beneficial versus …
ROCK inhibition modulates the senescence‐associated secretory phenotype (SASP) in oral keratinocytes
S Niklander, D Bandaru, DW Lambert… - FEBS Open Bio, 2020 - Wiley Online Library
… senescent cells, we treated normal (NOK805) and dysplastic (D6) senescent oral keratinocytes
… First, we wanted to assess whether Y-27632 was able to rescue senescent keratinocytes …
… First, we wanted to assess whether Y-27632 was able to rescue senescent keratinocytes …
[HTML][HTML] Mitochondrial dysfunction induces senescence with a distinct secretory phenotype
… senescence permanently arrests cell proliferation, often accompanied by a multi-faceted
senescence-associated secretory phenotype (… and stimulated keratinocyte differentiation in cell …
senescence-associated secretory phenotype (… and stimulated keratinocyte differentiation in cell …
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