The role of activation functions 1 and 2 of estrogen receptor‐α for the effects of estradiol and selective estrogen receptor modulators in male mice
AE Börjesson, HH Farman, C Engdahl… - Journal of Bone and …, 2013 - academic.oup.com
… In this study, we have evaluated the roles of ERαAF‐1 and ERαAF‐2 in male mice for the
effects of E2 in bone, and some other major estrogen‐responsive tissues by analyzing mice …
effects of E2 in bone, and some other major estrogen‐responsive tissues by analyzing mice …
Sex and genotype determine the selective activation of neurochemically-distinct mechanisms of swim stress-induced analgesia
JS Mogil, JK Belknap - Pharmacology Biochemistry and Behavior, 1997 - Elsevier
… /kg) in female mice of all three strains and male B6 mice, and a higher dose of dizocilpine
(0.25 mg/kg) in female mice of all three strains and male D2 mice. Testing doses of naloxone …
(0.25 mg/kg) in female mice of all three strains and male D2 mice. Testing doses of naloxone …
[HTML][HTML] Selective activation of Gs signaling in adipocytes causes striking metabolic improvements in mice
… selective activation of G s signaling in mouse adipose tissues. Specifically, we generated a
novel mutant mouse … GPCR (GsD) selectively in adipose tissues (adipo-GsD mice). In these …
novel mutant mouse … GPCR (GsD) selectively in adipose tissues (adipo-GsD mice). In these …
Bone protection by estrens occurs through non–tissue-selective activation of the androgen receptor
SH Windahl, R Galien, R Chiusaroli… - The Journal of …, 2006 - Am Soc Clin Investig
… This is in contrast with the SERM, which had been specifically selected for its lack of effects
on the breast and uterus and whose safety in both female and male mice was confirmed in …
on the breast and uterus and whose safety in both female and male mice was confirmed in …
Selective activation of the hypothalamic vasopressinergic system in mice deficient for the corticotropin-releasing hormone receptor 1 is dependent on glucocorticoids
MB Müller, R Landgraf, J Preil, I Sillaber… - …, 2000 - academic.oup.com
… Taken together, we could demonstrate a selective activation of the hypothalamic
vasopressinergic, but not the oxytocinergic, system and its critical involvement in the maintenance of …
vasopressinergic, but not the oxytocinergic, system and its critical involvement in the maintenance of …
The androgen receptor is selectively involved in organization of sexually dimorphic social behaviors in mice
C Bodo, EF Rissman - Endocrinology, 2008 - academic.oup.com
… male mice with a mutation of their single copy of the AR gene (X Tfm Y) exhibit female-typical
preference behaviors. Unlike WT males … 31–34), are sexually dimorphic in mice and rats. In …
preference behaviors. Unlike WT males … 31–34), are sexually dimorphic in mice and rats. In …
The role of androgens in Sertoli cell proliferation and functional maturation: studies in mice with total or Sertoli cell-selective ablation of the androgen receptor
KAL Tan, K De Gendt, N Atanassova, M Walker… - …, 2005 - academic.oup.com
… Compared with controls, ARKO mice exhibited a progressive reduction in … mice, which lack
AR in all testicular cells, with SCARKO mice in which AR expression was deleted selectively …
AR in all testicular cells, with SCARKO mice in which AR expression was deleted selectively …
A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis
K De Gendt, JV Swinnen… - Proceedings of the …, 2004 - National Acad Sciences
… Using Cre/loxP technology, we have generated mice with a ubiquitous knockout of the AR
as well as mice with a selective AR knockout in Sertoli cells (SC) only. Mice with a floxed exon …
as well as mice with a selective AR knockout in Sertoli cells (SC) only. Mice with a floxed exon …
Differential stress-induced neuronal activation patterns in mouse lines selectively bred for high, normal or low anxiety
P Muigg, S Scheiber, P Salchner, M Bunck, R Landgraf… - PloS one, 2009 - journals.plos.org
… To our knowledge, corresponding mouse models selectively … to establish the HAB and LAB
mouse lines. This intra-line … adult male HAB (n = 14), LAB (n = 13) and NAB (n = 13) mice …
mouse lines. This intra-line … adult male HAB (n = 14), LAB (n = 13) and NAB (n = 13) mice …
Selective activation of AKAP150/TRPV1 in ventrolateral periaqueductal gray GABAergic neurons facilitates conditioned place aversion in male mice
X Bai, K Zhang, C Ou, B Nie, J Zhang, Y Huang… - Communications …, 2023 - nature.com
… However, activating or inhibiting glutamatergic neurons, or activating GABAergic neurons
cannot … In AKAP150 flox/flox mice and C57/B6J wild-type mice, cell-type-selective inhibition of …
cannot … In AKAP150 flox/flox mice and C57/B6J wild-type mice, cell-type-selective inhibition of …
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