Selective loss of estrogen receptor β in malignant human colon
EF Foley, AA Jazaeri, MA Shupnik, O Jazaeri, LW Rice - Cancer Research, 2000 - AACR
… estrogen replacement therapy on colon cancer. The estrogen receptor (ER) is required for the
action of estrogen… and transcriptional response to selective estrogen response modulators. …
action of estrogen… and transcriptional response to selective estrogen response modulators. …
Therapeutic potential of selective estrogen receptor modulators
JÅ Gustafsson - Current opinion in chemical biology, 1998 - Elsevier
… one estrogen receptor and that an estrogenic agent was definitively categorized as an estrogen
… More recently we have learnt that there are two estrogen receptors which, under certain …
… More recently we have learnt that there are two estrogen receptors which, under certain …
Selective estrogen receptor modulation: concept and consequences in cancer
VC Jordan - Cancer cell, 2004 - cell.com
… site-specific actions of the selective estrogen receptor modulators tamoxifen and raloxifene.
The known beneficial or negative actions of selective estrogen receptor modulators (SERMs) …
The known beneficial or negative actions of selective estrogen receptor modulators (SERMs) …
Selective estrogen receptor modulation: a personal perspective
VC Jordan - Cancer research, 2001 - AACR
… Wolf DM, Jordan VC The estrogen receptor from a tamoxifen stimulated MCF-… estrogen
receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor…
receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor…
Selective estrogen receptor modulators: an alternative to hormone replacement therapy
HU Bryant, WH Dere - Proceedings of the Society for …, 1998 - journals.sagepub.com
… estrogen receptor, agents displaying this tissue selective profile were later classified as
selective estrogen receptor … a distinct pharmacological profile from full estrogens (ie, ICI- 164,384…
selective estrogen receptor … a distinct pharmacological profile from full estrogens (ie, ICI- 164,384…
Selective estrogen receptor modulators: structure, function, and clinical use
CK Osborne, H Zhao, SAW Fuqua - Journal of clinical oncology, 2000 - ascopubs.org
… estrogen that are mediated through the estrogen receptor (ER). However, these drugs also
have many estrogenic … are more appropriately called selective estrogen receptor modulators (…
have many estrogenic … are more appropriately called selective estrogen receptor modulators (…
The use of selective estrogen receptor modulators and selective estrogen receptor down-regulators in breast cancer
… of agents: the selective estrogen receptor … selective estrogen receptor down-regulators
(SERDs; eg fulvestrant (ICI 182780), SR 16234 and ZK 191703) also termed ‘pure anti-estrogens’…
(SERDs; eg fulvestrant (ICI 182780), SR 16234 and ZK 191703) also termed ‘pure anti-estrogens’…
Beyond estrogen: advances in tissue selective estrogen complexes and selective estrogen receptor modulators
JV Pinkerton, EA Conner - Climacteric, 2019 - Taylor & Francis
… to treat resistant estrogen receptor-positive breast cancer in women. Estetrol is an estrogen
… and initially considered a weak estrogen, but it appears to have dual weak estrogenic/anti-…
… and initially considered a weak estrogen, but it appears to have dual weak estrogenic/anti-…
Selective estrogen receptor modulators: tissue specificity and clinical utility
… Selective estrogen receptor modulators (SERMs) are a diverse group of nonsteroidal
compounds that function as agonists or antagonists for estrogen receptors (ERs) in a target gene-…
compounds that function as agonists or antagonists for estrogen receptors (ERs) in a target gene-…
Selective estrogen receptor modulators (SERMS)
A Diez-Perez - Arquivos Brasileiros de Endocrinologia & Metabologia, 2006 - SciELO Brasil
… , estrogen and SERMS exert different effects on estrogen … Although the mechanism of
activation of estrogen receptor is … of selective "a la carte" ligands for different hormone receptors. …
activation of estrogen receptor is … of selective "a la carte" ligands for different hormone receptors. …
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