… Here we show that blockade of p38 MAPK by the p38 inhibitor SB 203580 also inhibited
the LPS-stimulated generation of TNF-α and MIP-2, whereas once again the CC chemokine …

… ), a highly selective p38α MAPK inhibitor [26], for its effects on p38α MAPK activity and tau
… We report here that MW181 suppresses p38α MAPK activation, reduces tau phosphorylation…

… p38 MAPK activation is increased in the lungs of COPD patients, and p38 MAPK inhibitors
suppress … However, p38 MAPK inhibitors have shown variable effects in COPD clinical trials, …

… was accomplished with the compound M39, which is a highly selective and bioavailable
inhibitor of p38 MAPK (28). Herein we report the effect of poststimulation inhibition of …

… Here, we discuss alternative strategies that might lead to better p38 inhibitors, including
non-ATP-competitive inhibitors and inhibitors that are targeted to other components of the …

… regulated/activated kinase (PRAK), which are selectively phosphorylated by p38 MAPK. …
plays multiple roles in physiological systems other than inflammation, suppression of this kinase …

… selective inhibitors of p38 MAP kinase. SB 203580 inhibits the catalytic activity of p38 MAP
kinase … may be involved in mediating IL-10-induced effects (eg, suppression of tumor necrosis …

… Selective inhibitors of p38 MAPK, mainly the α isoform, have been developed. In seeking …
p38 MAPK activation in corticosteroid sensitivity, we examined whether inhibitors of p38 MAPK …

… These isoforms differ in tissue distributions, regulation by upstream stimuli, and selectivity …
Raf–MEK–ERK MAPK pathway and the stress-induced MINK–MKK3/6–p38–PRAK …

… We have studied the role of ERK and p38 mitogen-activated … of ERK and p38 MAP kinase
inhibitors. Furthermore, … that inhibition of p38 MAP kinase selectively destabilizes TNF-…