65 天前 - … Laro is the first-in-class, highly selective, central nervous system (CNS)-active
TRK inhibitor approved for tumor-agnostic use in pts with TRK fusion cancer based on overall …

93 天前 - … of thyroid carcinoma has … thyroid cancer, including active surveillance for DTCs <1
cm, 1,2 hemithyroidectomy for intrathyroidal, nonmetastatic DTCs <4 cm, and selective use of …

163 天前 - … The selective AKT inhibitor MK2206 was noted to reverse the increased expression
of p-AKT (ser473) and p-GSK3α/β (ser21/9) induced by PFKFB3 overexpression. The level …

175 天前 - … • The neoadjuvant use of selective RET inhibitors is a promising approach in locally
… thyroid carcinoma, while RET fusions are identified in 5-10% of papillary thyroid carcinomas…

194 天前 - … thyroid cancers (excluding anaplastic thyroid carcinoma) remain undefined. About
60% of medullary thyroid … Little is currently known regarding the safety of selective RET …

275 天前 - … ) is a highly selective rearranged during transfection (RET) … thyroid carcinoma or
non-small cell lung carcinoma. Among … who had medullary thyroid carcinoma with RET M918T …

302 天前 - … on treatment of thyroid carcinomas arising from … thyroid lobectomy or pyramidal
lobe resection 3) SP with total or near total thyroidectomy in all patients and 4) SP and selective …

310 天前 - … Sampling a multinodular goiter should be ented, and each level should be carefully
dissected limited to one or two sections selectively taken (see Chapter 10). Each lymph …

354 天前 - … The discovery of driver oncogenes for thyroid carcinomas … have altered the treatment
algorithm in thyroid cancer (TC), … number of selective RET inhibitors approved for use, this …