[HTML][HTML] Self-assembling, self-adjuvanting and fully synthetic peptide nanovaccine for cancer immunotherapy

H Song, Q Su, P Huang, C Zhang, W Wang - Smart Materials in Medicine, 2021 - Elsevier
… for manufacturing self-assembled, self-adjuvanting, and fully synthetic peptide vaccines
and … nanovaccines prepared by co-assembly strategy as the future development of peptide

Self-adjuvanting cancer nanovaccines

Z Liao, J Huang, PC Lo, JF Lovell, H Jin… - Journal of …, 2022 - Springer
… To further elucidate the role of self-adjuvanting nanovaccinesadjuvants with respect to
nanovaccines with self-adjuvanting … free peptide vaccine and Alum-adjuvanted vaccine, this self-…

Poly (amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines

M Skwarczynski, G Zhao, JC Boer, V Ozberk… - Science …, 2020 - science.org
… Herein, we propose a self-adjuvanting peptide-based vaccine delivery system designed
to overcome these disadvantages. This system is based on fully defined and biodegradable …

Systematic Evaluation of Self-Adjuvanting Lipopeptide Nano-Vaccine Platforms for the Induction of Potent CD8+ T-cell Responses

SH Apte, RJ Stephenson, P Simerska, PL Groves… - …, 2016 - Taylor & Francis
… Materials & methods: Three different self-adjuvanting lipid core peptide nanovaccines each
comprising four copies of the dominant ovalbumin CD8 + T-cell epitope and varying in the …

A Fluorinated Supramolecular Self‐Assembled Peptide as Nanovaccine Adjuvant for Enhanced Cancer Vaccine Therapy

S Jia, S Ji, J Zhao, Y Lv, J Wang, D Sun… - Small …, 2023 - Wiley Online Library
… including Alum and CpG, 4RDP(F5)-OVA nanovaccine demonstrated better … adjuvants,
expanded the diversity of peptide adjuvants, and might provide an attractive vaccine adjuvant

Self-assembly M2e-based peptide nanovaccine confers broad protection against influenza viruses

Q Wang, Y Zhang, P Zou, M Wang, W Fu… - Frontiers in …, 2020 - frontiersin.org
… We observed that aluminum-adjuvant-M2e peptide vaccine also induced … peptide-based
nanovaccines is that peptides can be synthesized in high purity by current solid-phase peptide

Designing self-assembled peptide nanovaccine against Streptococcus pneumoniae: an in silico strategy

H Dorosti, M Eslami, N Nezafat, F Fadaei… - Molecular and cellular …, 2019 - Elsevier
… an adjuvant to the vaccine [9], and the recent strategy is applying self-assembled peptide
In some cases, the low efficacy of epitope peptide-based vaccines may be according to their …

A new polysaccharide platform constructs self-adjuvant nanovaccines to enhance immune responses

S Chen, L Yang, X Ou, JY Li, CT Zi, H Wang… - Journal of …, 2022 - Springer
… to assemble with other bioactive molecules such as peptides, proteins and nucleic acid [7,
8]. … as a versatile platform to construct diverse types of self-adjuvant nanovaccines is feasible. …

Targeting dendritic cells in lymph node with an antigen peptide-based nanovaccine for cancer immunotherapy

Y Qian, H Jin, S Qiao, Y Dai, C Huang, L Lu, Q Luo… - Biomaterials, 2016 - Elsevier
… Altogether, these results demonstrate the effectiveness of α-Ap-NP-CpG as a potent
therapeutic nanovaccine that can successfully co-load Ap and adjuvant and deliver them to the …

A simple self-adjuvanting biomimetic nanovaccine self-assembled with the conjugate of phospholipids and nucleotides can induce a strong cancer …

D Liu, J Liu, B Ma, B Deng, X Leng, D Kong… - Biomaterials Science, 2021 - pubs.rsc.org
… a simple self-adjuvanting biomimetic nanovaccine (NaV) self-… of DOPE and hydrophilic
adjuvanting Toll-like receptor (TLR9) … membrane self-assembled forming nanocapsules. So, the …