The protective effect of operant social reward on cocaine self-administration, choice, and relapse is dependent on delay and effort for the social reward

M Venniro, LV Panlilio, DH Epstein… - …, 2021 - nature.com
… we parametrically manipulate the delay and response requirement (effort) to obtain the social
reward. Based on results from a recent study [32], we also delayed access to both cocaine …

Effects of altering reinforcer magnitude and reinforcement schedule on phencyclidine (PCP) self-administration in monkeys using an adjusting delay task

JL Newman, JL Perry, ME Carroll - Pharmacology Biochemistry and …, 2008 - Elsevier
… For Experiment 2, we hypothesized that increasing the amount of effort required to obtain …
monkeys discounted delayed self-administered oral deliveries of PCP using an adjusting delay

Suppression of cocaine self-administration in monkeys: effects of delayed punishment

WL Woolverton, KB Freeman, J Myerson, L Green - Psychopharmacology, 2012 - Springer
… results may serve as a reminder that the negative consequences of substance abuse are
governed by similar principles, and these principles must be taken into account in our effort to …

Performance in a computerized self-control task by rhesus macaques (Macaca mulatta): The combined influence of effort and delay

TA Evans - Learning and Motivation, 2007 - Elsevier
… Thus, from these studies we can conclude that delay and effort affect self-control in a similar
… that delay and effort training effects do not generalize across delay and effort requirements, …

[HTML][HTML] Delay aversion but preference for large and rare rewards in two choice tasks: implications for the measurement of self-control parameters

W Adriani, G Laviola - BMC neuroscience, 2006 - Springer
… , however, a clear dissociation has been reported between delay and probability discounting.
… All efforts were made to minimize animal suffering, to reduce the number of animals used, …

Prior cocaine self-administration does not impair the ability to delay gratification in rats during diminishing returns

HJ Pribut, N Kang, MR Roesch - Behavioural Pharmacology, 2024 - journals.lww.com
… requires little effort or time to achieve a reward and another that requires more effort or time
to … rats that previously self-administered cocaine exhibit greater sensitivity to delays after the …

Preexposure to MDMA (“Ecstasy”) delays acquisition but facilitates MDMA-induced reinstatement of amphetamine self-administration behavior in rats

KC Morley, JL Cornish, KM Li, IS McGregor - … Biochemistry and Behavior, 2004 - Elsevier
… of intravenous amphetamine self-administration and the … Intravenous self-administration
of low dose d-amphetamine (… slower to acquire amphetamine self-administration. However, …

[HTML][HTML] Dopamine and acetylcholine have distinct roles in delay-and effort-based decision-making in humans

M Erfanian Abdoust, MI Froböse, A Schnitzler… - Plos …, 2024 - journals.plos.org
… number for both the effort and delay discounting task (trial number effect on effort discounting:
HDI Mean = −0.60, HDI 95% = [−0.75; −0.46]; trial number effect on delay discounting: HDI …

Progressive-ratio schedules of drug delivery in the analysis of drug self-administration: a review

D Stafford, MG LeSage, JR Glowa - Psychopharmacology, 1998 - Springer
… as tools in the analysis of drug self-administration. Progressive-ratio schedules of drug
delivery … can influence the reinforcing efficacy of self-administered drugs. The objectives of this …

Amping up effort: effects of d-amphetamine on human effort-based decision-making

MC Wardle, MT Treadway, LM Mayo… - Journal of …, 2011 - Soc Neuroscience
delay rather than effort costs. In some animal studies, amphetamine only increased willingness
to exert effort when delays … willingness to exert effort even when delays were equalized; …