[HTML][HTML] Strategies for targeting senescent cells in human disease
NS Gasek, GA Kuchel, JL Kirkland, M Xu - Nature aging, 2021 - nature.com
… of senescence to emphasize how senescent cells are currently … further compounded by the
senescent cell secretome. Finally, … for targeting various types of senescent cells as well as the …
senescent cell secretome. Finally, … for targeting various types of senescent cells as well as the …
Senescent cells: an emerging target for diseases of ageing
BG Childs, M Gluscevic, DJ Baker… - Nature reviews Drug …, 2017 - nature.com
… human disease. One plausible explanation for this correlation is that mechanisms that drive
ageing might also promote age-related diseases. … on two major human diseases of ageing, …
ageing might also promote age-related diseases. … on two major human diseases of ageing, …
Senescent cells: emerging targets for human aging and age-related diseases
S Song, EWF Lam, T Tchkonia, JL Kirkland… - Trends in biochemical …, 2020 - cell.com
… extending human healthspan. Here, we review molecular links between cellular senescence
and … avenues that may be exploited to target senescent cells in future geriatric medicine. …
and … avenues that may be exploited to target senescent cells in future geriatric medicine. …
Senescent cells: a novel therapeutic target for aging and age‐related diseases
RM Naylor, DJ Baker… - Clinical Pharmacology & …, 2013 - Wiley Online Library
… of senescent cells to human disease and to explore the preventive and therapeutic effects of
clearing senescent cells by … for chronic age-related human diseases with INK-ATTAC mice. …
clearing senescent cells by … for chronic age-related human diseases with INK-ATTAC mice. …
The role of senescent cells in ageing
JM Van Deursen - Nature, 2014 - nature.com
… , and induction of senescence in neighbouring cells (paracrine senescence). An … cells that
develop key properties of senescent cells might contribute to ageing and age-related disease …
develop key properties of senescent cells might contribute to ageing and age-related disease …
[HTML][HTML] Senescent cells: a therapeutic target for cardiovascular disease
BG Childs, H Li, JM Van Deursen - The Journal of clinical …, 2018 - Am Soc Clin Investig
… Here, we review the evidence that cellular senescence drives … for disease and driving
established disease forward. Hence, the growing field of senotherapy (neutralizing senescent cells …
established disease forward. Hence, the growing field of senotherapy (neutralizing senescent cells …
[HTML][HTML] Targeting senescent cells: approaches, opportunities, challenges
C Von Kobbe - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
… -related diseases. Current therapies are focused on elimination of senescent cell functions in
… such as cancer and arthrosis [83], which are aging-related diseases where senescent cells …
… such as cancer and arthrosis [83], which are aging-related diseases where senescent cells …
[HTML][HTML] Senescent cells as promising targets to tackle age-related diseases
E Prašnikar, J Borišek, A Perdih - Ageing Research Reviews, 2021 - Elsevier
… diseases and therefore a potential therapeutic target. Here, the role of senescent cells in
age-related diseases is … The mechanisms leading to senescent cells are presented, including …
age-related diseases is … The mechanisms leading to senescent cells are presented, including …
Quantitative identification of senescent cells in aging and disease
A Biran, L Zada, P Abou Karam, E Vadai, L Roitman… - Aging cell, 2017 - Wiley Online Library
… of senescent cells are challenging tasks that limit our understanding of the role of senescent
cells in diseases … senescent cells in tissues on a single-cell basis. The method combines a …
cells in diseases … senescent cells in tissues on a single-cell basis. The method combines a …
[图书][B] Cells, aging, and human disease
MB Fossel - 2004 - books.google.com
… The ubiquity of disease is no more ordained than is the rarity … how diseases of aging occur,
that we may prevent human … Virally transformed senescent cells reactivate DNA synthesis …
that we may prevent human … Virally transformed senescent cells reactivate DNA synthesis …
相关搜索
- senescent cells human aging
- senescent cells therapeutic target
- senescent cells cardiovascular disease progression
- senescent cell burden
- role of senescent cells
- senescent cells era of global aging
- senescent cells promising targets
- senescent cells quantitative identification
- senescent cells translational medicine
- senescent cells dark side
- cellular senescence neurodegenerative diseases
- cellular senescence cardiac diseases
- hallmarks of cellular senescence
- cellular senescence and ageing
- cellular senescence in vivo
- cellular senescence in vitro