[HTML][HTML] Clinical and genetic predictors of prognosis in myelodysplastic syndromes

R Bejar - Haematologica, 2014 - ncbi.nlm.nih.gov
… the prediction of prognosis for myelodysplastic syndrome patients … the care of patients with
myelodysplastic syndromes. … poor sensitivity to detect small subclones and most patients with …

… lineage-specific chimerism analysis is a sensitive predictor of relapse in patients with acute myeloid leukemia and myelodysplastic syndrome after allogeneic stem …

J Mattsson, M Uzunel, L Tammik, J Aschan, O Ringden - Leukemia, 2001 - nature.com
… leukemia and myelodysplastic syndrome after SCT. In order to improve sensitivity and …
In this study, chimerism analysis showed a higher sensitivity and specificity vsmorphological …

Flow cytometric detection of dyserythropoiesis: a sensitive and powerful diagnostic tool for myelodysplastic syndromes

S Mathis, N Chapuis, C Debord, A Rouquette… - Leukemia, 2013 - nature.com
… Phase III is a pragmatic one aiming at developing a diagnostic score using these markers
and evaluating its diagnostic properties (sensitivity, specificity and predictive values) in routine …

Early detection of relapse in patients with myelodysplastic syndrome after allo-SCT

M Tobiasson, R Olsson, E Hellström-Lindberg… - Bone marrow …, 2011 - nature.com
… rule out that MC is a useful predictor of relapse in this setting. … in patients with MDS is a
sensitive method that enables early … in primary myelodysplastic syndrome are highly predictive of …

[PDF][PDF] Predicting survival and leukemic evolution in patients with myelodysplastic syndrome

L Malcovati, MG Della Porta, M Cazzola - Haematologica, 2006 - haematologica.org
predictive value for the outcome when marrow lineage involvement was included the analysis.
The only IPSS variable that maintains a prognostic value in MDS patients … of MDS patients …

Real-time assessment of relapse risk based on the WT1 marker in acute leukemia and myelodysplastic syndrome patients after hematopoietic cell transplantation

A Israyelyan, L Goldstein, W Tsai, L Aquino… - Bone marrow …, 2015 - nature.com
… 82 leukemia and MDS patients and defined specific molecular ratios for relapse prediction.
The … 100% specificity and 75% sensitivity reliably predicting future relapse with an observed …

[HTML][HTML] … detected by geriatric and quality of life assessment in 195 older patients with myelodysplastic syndromes and acute myeloid leukemia are highly predictive for …

B Deschler, G Ihorst, U Platzbecker, U Germing… - …, 2013 - ncbi.nlm.nih.gov
… It has been suggested that this is more sensitive than the Karnofsky Index for assessing …
health status/QOL have repeatedly been the best predictors of survival. In this context, Oliva et al. …

[HTML][HTML] … limitations of donor T cell chimerism after myeloablative allogeneic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndromes

E Wong, K Mason, J Collins, B Hockridge… - Biology of Blood and …, 2017 - Elsevier
… The primary objective of the study was to evaluate the sensitivity and specificity of day 100
donor T cell chimerism (D100chim) as a predictor of RFS 6 months (RFS6) and 12 months (…

Prognostic models in myelodysplastic syndromes

R Bejar - Hematology 2013, the American Society of …, 2013 - ashpublications.org
… the prediction of prognosis of particular importance for MDS … various methods for predicting
the prognosis of MDS patients. … very low levels and will require sensitive techniques to detect. …

TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients

R Bejar, A Lord, K Stevenson… - Blood, The Journal …, 2014 - ashpublications.org
… and more sensitive multigene analysis similarly identified TET2 mutations as predictive of …
Surprisingly, consideration of mutations in other genes did not reveal additional predictors of …