Kidney biopsy is a sensitive tool for retrospective diagnosis of PLA2R-related membranous nephropathy

B Svobodova, E Honsova, P Ronco… - Nephrology Dialysis …, 2013 - academic.oup.com
… activity in patients with idiopathic membranous nephropathy (iMN). To determine the most
sensitive test for the diagnosis of PLA2R-related membranous nephropathy (MN) irrespective …

Advances in membranous nephropathy

P Ronco, E Plaisier, H Debiec - Journal of Clinical Medicine, 2021 - mdpi.com
Membranous nephropathy (MN) is a rare disease affecting the glomerular capillary wall,
which plays a key role in controlling permeability to proteins. It accounts for about 20% of cases …

Membranous nephropathy

P Ronco, L Beck, H Debiec, FC Fervenza… - Nature reviews Disease …, 2021 - nature.com
… pure lupus MN (LMN; also referred to class V lupus nephropathy) and in around the same
percentage of mixed class lupus nephropathy, that is, class III or class IV associated with class …

Membranous nephropathy: a journey from bench to bedside

JM Francis, LH Beck Jr, DJ Salant - American Journal of Kidney Diseases, 2016 - Elsevier
… subepithelial deposits in kidney tissue is a very sensitive and specific technique to diagnose
PLA 2 … MN, with sensitivity of 83% and specificity > 90%, 84 making this test an ideal tool for …

Primary membranous nephropathy: comprehensive review and historical perspective

KC Keri, S Blumenthal, V Kulkarni… - Postgraduate …, 2019 - academic.oup.com
Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in non-…
that has promising evidence to be used as a tool to prognosticate the course of the disease. …

The diagnosis accuracy of PLA2R-AB in the diagnosis of idiopathic membranous nephropathy: a meta-analysis

Y Du, J Li, F He, Y Lv, W Liu, P Wu, J Huang, S Wei… - PloS one, 2014 - journals.plos.org
… Although PLA2R-AB may be a new tool for iMN diagnosis, its efficacy still remains … sensitivity
and specificity of PLA2R-AB testing in patients with idiopathic membranous nephropathy. …

Pathophysiological advances in membranous nephropathy: time for a shift in patient's care

P Ronco, H Debiec - The Lancet, 2015 - thelancet.com
Membranous nephropathy is a major cause of nephrotic syndrome of non-diabetic origin in
… the pathogenesis of the disease and absence of sensitive biomarkers of disease activity. The …

Membranous nephropathy: diagnosis, treatment, and monitoring in the post-PLA2R era

L Safar-Boueri, A Piya, LH Beck, R Ayalon - Pediatric Nephrology, 2021 - Springer
… serve as a useful diagnostic and monitoring tool in this younger population as well… sensitivity
and specificity for the recognition of PLA2R/THSD7A-associated membranous nephropathy

Diagnostic utility of serum and urine biomarkers in idiopathic membranous nephropathy: a systematic review and meta-analysis

D Gao, LP Lu, ZG Zhao - International Urology and Nephrology, 2023 - Springer
… Therefore, there was a high level of heterogeneity in the sensitivity of our meta-analysis (I
2 = 88.47%), probably due to the region of studies, test method, specimen type, control group …

Primary membranous nephropathy

WG Couser - Clinical Journal of the American Society of …, 2017 - journals.lww.com
Membranous nephropathy (MN) is a unique glomerular lesion that is the most common
cause of idiopathic nephrotic syndrome in nondiabetic white adults. About 80% of cases are …