Diagnostic value of phospholipase A2 receptor in idiopathic membranous nephropathy: a systematic review and meta-analysis

SL Hu, D Wang, WJ Gou, QF Lei, TA Ma… - Journal of nephrology, 2014 - Springer
… idiopathic membranous nephropathy (IMN), but there are limited data about the sensitivity and
… This revised tool is a considerable improvement from the original tool as it allows for more …

Pathogenesis of membranous nephropathy: recent advances and future challenges

P Ronco, H Debiec - Nature Reviews Nephrology, 2012 - nature.com
… , with particular emphasis on the antibodies involved because they provide new tools for …
kidneys of patients with membranous nephropathy because of a lack of sensitive methods. The …

A proposal for a serology-based approach to membranous nephropathy

AS De Vriese, RJ Glassock, KA Nath… - Journal of the …, 2017 - journals.lww.com
… CBA-IFA is a more sensitive technique for the detection of very … ; this threshold improves
sensitivity but will obviously lead to … We recognize that the diagnostic tools in this algorithm, in …

Immunology of membranous nephropathy: from animal models to humans

RA Sinico, N Mezzina, B Trezzi… - Clinical & …, 2016 - academic.oup.com
… emerged as a specific and sensitive biomarker of idiopathic membranous nephropathy. …
antibodies is becoming a monitoring tool of immunological activity of idiopathic membranous

[PDF][PDF] Anti-PLA2R-associated membranous nephropathy: a review with emphasis on diagnostic testing methods

C VanBeek, M Haas - Clin Nephrol, 2015 - academia.edu
… The majority of cases of primary membranous nephropathy (… ing PLA2R testing as a tool in
the diagnosis and management of … Kidney biopsy is a sensitive tool for retrospective diagnosis …

Membranous nephropathy—diagnosis and identification of target antigens

S Sethi, FC Fervenza - Nephrology Dialysis Transplantation, 2024 - academic.oup.com
… The ELISA assay provides quantification of antibody titers, and is 70% sensitive and 99.6%
specific for MN. The IFA test provides a sensitivity of 77.1% and a specificity of 100%, but is …

[HTML][HTML] Membranous nephropathy: a review on the pathogenesis, diagnosis, and treatment

WL Lai, TH Yeh, PM Chen, CK Chan… - Journal of the Formosan …, 2015 - Elsevier
In adults, membranous nephropathy (MN) is a major cause of nephrotic syndrome. However,
the etiology of approximately 75% of MN cases is idiopathic. Secondary causes of MN are …

Antigen identification in membranous nephropathy moves toward targeted monitoring and new therapy

P Ronco, H Debiec - Journal of the American Society of …, 2010 - journals.lww.com
tools for monitoring human disease activity and should be of value in designing new
antigen-driven therapeutic strategies. Membranous nephropathy is … developed a sensitive enzyme-…

Diagnostic accuracy of PLA2R autoantibodies and glomerular staining for the differentiation of idiopathic and secondary membranous nephropathy: an updated meta …

H Dai, H Zhang, Y He - Scientific reports, 2015 - nature.com
… The summary point represents the summary sensitivity and specificity, the … sensitivity and
specificity and the 95% prediction region represents the 95% confidence interval of sensitivity

GWAS-based discoveries in IgA nephropathy, membranous nephropathy, and steroid-sensitive nephrotic syndrome

E Sanchez-Rodriguez, CT Southard… - Clinical Journal of the …, 2021 - journals.lww.com
… (GWAS) have emerged as a powerful tool to understand the genetic basis of complex traits
… IgA nephropathy, membranous nephropathy, and steroid-sensitive nephrotic syndrome. IgA …