Using sensitivity analysis to develop a validated computational model of post-operative calvarial growth in sagittal craniosynostosis

C Cross, RH Khonsari, L Galiay… - Frontiers in Cell and …, 2021 - frontiersin.org
… -operative predictions of craniosynostosis outcomes. … of sensitivity studies to understand
the effect of various input parameters on predicting the skull morphology of a sagittal synostosis

Predicting and comparing three corrective techniques for sagittal craniosynostosis

C Cross, RH Khonsari, D Larysz, D Johnson, L Kölby… - Scientific Reports, 2021 - nature.com
… A sensitivity test was carried out to investigate the effect of altering the initial spring force
values by updating the spring stiffness on the predicted morphology (see: Supplementary Table …

Predicting calvarial morphology in sagittal craniosynostosis

O Malde, C Cross, CL Lim, A Marghoub… - Scientific Reports, 2020 - nature.com
… finite element model of a sagittal craniosynostosis. Here, the … and we need to understand
the sensitivity of these models to … model of a case of sagittal craniosynostosis. Here, the finite …

Making the diagnosis in sagittal craniosynostosis—it's height, not length, that matters

JD Blum, DY Cho, L Cheung, DF Villavisanis, J Ng… - Child's Nervous …, 2022 - Springer
… This investigation demonstrates the promising sensitivity and specificity of a novel clinical
tool for the diagnosis of sagittal craniosynostosis in a sample of 307 patients. The VNO angle …

Children with suspected craniosynostosis: a cost-effectiveness analysis of diagnostic strategies

LS Medina, RR Richardson… - American Journal of …, 2002 - Am Roentgen Ray Soc
… Two-way sensitivity analysis for the variable pretest probability of craniosynostosis is shown
in Figure 2. This analysis showed a significant decrease in the cost per QALY gained for 3D …

A systematic approach to predicting spring force for sagittal craniosynostosis surgery

G Zhang, H Tan, X Qian, J Zhang, K Li… - Journal of …, 2016 - journals.lww.com
… These results are consistent with our sensitivity analysis in the above section. For the
SVR-trained model, we obtained SVR weights θ in Eq. (4) for each feature and ranked features …

Management of sagittal craniosynostosis: morphological comparison of eight surgical techniques

L Galiay, Q Hennocq, C Cross, E Arnaud… - British Journal of Oral …, 2022 - Elsevier
… of sagittal synostosis versus a large cohort of control patients. Computed tomographic (CT)
images were obtained from children CT-scanned for non-craniosynostosis related events (n = …

A population-specific material model for sagittal craniosynostosis to predict surgical shape outcomes

A Borghi, N Rodriguez Florez, F Ruggiero… - … and modeling in …, 2020 - Springer
… Newborns affected by premature closure of the sagittal suture (sagittal craniosynostosis—SC)
develop an elongated and narrow head because of compensatory growth of the skull in …

Sagittal craniosynostosis outcome assessment for two methods and timings of intervention

J Panchal, JL Marsh, TS Park, B Kaufman… - Plastic and …, 1999 - journals.lww.com
… measurements sensitive to cranial width and length (cranial index)." A retrospective
quantitative analysis of 40 infants who underwent surgery for sagittal craniosynostosis, therefore, …

A computational framework to predict calvarial growth: optimising management of sagittal craniosynostosis

C Cross, RH Khonsari, G Patermoster… - … in Bioengineering and …, 2022 - frontiersin.org
… In summary, we believe the presented approach provides a sustainable way of assisting
with preoperative sagittal craniosynostosis management and estimating the postoperative …