Leukocyte apoptosis and its significance in sepsis and shock

DE Wesche, JL Lomas-Neira, M Perl… - Journal of leukocyte …, 2005 - academic.oup.com
… neutrophils in the shocked and/or septic animal. This delayed neutrophil apoptosis seems to
be … Antiapoptotic members of the Bcl-2 family can inhibit apoptosis through the intrinsic and …

Apoptosis in sepsis

R Mahidhara, TR Billiar - Critical care medicine, 2000 - journals.lww.com
… linking dysfunction of neutrophil apoptosis with sepsis is that delays in neutrophil … the
normal time course of neutrophil apoptosis in some, but not all, models of sepsis. In vivo studies …

Upregulation of reactive oxygen species generation and phagocytosis, and increased apoptosis in human neutrophils during severe sepsis and septic shock

PS Martins, EG Kallas, MC Neto, MA Dalboni… - Shock, 2003 - journals.lww.com
… In this study, we evaluated neutrophil activation in severe sepsis and septic shock by measuring
its phagocytic ability and oxidative burst activity. We also evaluated neutrophil apoptosis

Histopathology of septic shock induced acute kidney injury: apoptosis and leukocytic infiltration

N Lerolle, D Nochy, E Guérot, P Bruneval… - Intensive care …, 2010 - Springer
… lumens by leucocytes, predominantly monocytic; (3) apoptosis of … The marked increase in
apoptosis and capillary leukocytic … for a role for them in the pathogenesis of AKI in septic shock. …

Cellular apoptosis and organ injury in sepsis: a review

C Power, N Fanning, HP Redmond - Shock, 2002 - journals.lww.com
neutrophil apoptosis in vitro ( 54,55 ). Monocytes and neutrophils activated in the inflammatory
response have also been shown to produce IL-1β and TNF-α ( 54,55 )), suggesting that …

Evolution of neutrophil apoptosis in septic shock survivors and nonsurvivors

E Tamayo, E Gómez, J Bustamante… - Journal of critical …, 2012 - Elsevier
… In conclusion, over the first 12 days of septic shock development, the level of neutrophil
apoptosis decreased and did not return to normal values, with no difference between surviving …

Neutrophil apoptosis: a marker of disease severity in sepsis and sepsis-induced acute respiratory distress syndrome

L Fialkow, L Fochesatto Filho, MC Bozzetti, AR Milani… - Critical Care, 2006 - Springer
… ]) may limit inflammatory injury in sepsis and acute respiratory … the severity of sepsis and
extent of PMN apoptosis and the … neutrophil apoptosis with the severity of sepsis and sepsis-…

Apoptosis in sepsis: a new target for therapeutic exploration

C Oberholzer, A Oberholzer, M Clare-Salzler… - The FASEB …, 2001 - Wiley Online Library
sepsis can delay neutrophil apoptosis and delayed neutrophil apoptosis has been associated
with severe clinical sepsis (… In trauma patients, neutrophil apoptosis correlated with MODS …

Pathological aspects of apoptosis in severe sepsis and shock?

A Ayala, JL Lomas, PS Grutkoski, CS Chung - The International Journal of …, 2003 - Elsevier
… with a high incidence of patients who develop sepsis and subsequent multiple organ failure.
This … of apoptosis, but begins to define its contribution to the pathology of sepsis and shock, …

The prognostic value of leukocyte apoptosis in patients with severe sepsis at the emergency department

CT Kung, CM Su, HW Chang, HH Cheng, SY Hsiao… - Clinica Chimica …, 2015 - Elsevier
… Cell apoptosis in critically ill patients plays a pivotal role in the … of sepsis. This study
aimed to determine the prognostic value of leukocyte apoptosis in patients with severe sepsis. …