Modulating neutrophil apoptosis
JC Marshall, Z Malam, S Jia - Sepsis: New Insights, New …, 2006 - Wiley Online Library
… Taneja R, Parodo J, Kapus A, Rotstein OD, Marshall JC 2004 Delayed neutrophil apoptosis
in sepsis is associated with maintenance of mitochondrial transmembrane potential (DYM) …
in sepsis is associated with maintenance of mitochondrial transmembrane potential (DYM) …
Circulating mediators in serum of injured patients with septic complications inhibit neutrophil apoptosis through up-regulation of protein-tyrosine phosphorylation
W Ertel, M Keel, M Infanger, U Ungethum… - Journal of Trauma …, 1998 - journals.lww.com
… investigating the mechanisms by which serum of trauma patients with sepsis, but not trauma
alone, inhibits neutrophil apoptosis. These studies also documented that the suppression in …
alone, inhibits neutrophil apoptosis. These studies also documented that the suppression in …
Pathophysiology of sepsis
DG Remick - The American journal of pathology, 2007 - Elsevier
… However, patients with sepsis have a delay in their neutrophil apoptosis, causing them to
persist longer in the bloodstream. This is due to prolonged activation of nuclear factor κB and …
persist longer in the bloodstream. This is due to prolonged activation of nuclear factor κB and …
Pre–B cell colony–enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis
SH Jia, Y Li, J Parodo, A Kapus, L Fan… - The Journal of …, 2004 - Am Soc Clin Investig
… a requisite role in the delayed neutrophil apoptosis of clinical and experimental sepsis. … to
the inflammatory injury of sepsis. The inhibition of neutrophil apoptosis by LPS or inflammatory …
the inflammatory injury of sepsis. The inhibition of neutrophil apoptosis by LPS or inflammatory …
When apoptosis meets autophagy: deciding cell fate after trauma and sepsis
YC Hsieh, M Athar, IH Chaudry - Trends in Molecular Medicine, 2009 - cell.com
… on apoptosis after trauma–hemorrhage and sepsis. The inter-relationship between autophagy
and apoptosis might … for the detection and treatment of trauma–hemorrhage and sepsis. …
and apoptosis might … for the detection and treatment of trauma–hemorrhage and sepsis. …
Apoptosis in sepsis: mechanisms, clinical impact and potential therapeutic targets
A Ayala, M Perl, F Venet, J Lomas-Neira… - Current …, 2008 - ingentaconnect.com
… processes underpinning the development of sepsis if we are to … evidence in sepsis research
suggests that apoptosis in a variety … Leukocyte and endothelial cell interactions in sepsis: …
suggests that apoptosis in a variety … Leukocyte and endothelial cell interactions in sepsis: …
Role of HMGB1 in apoptosis-mediated sepsis lethality
S Qin, H Wang, R Yuan, H Li, M Ochani… - The Journal of …, 2006 - rupress.org
… -FMK, a broad-spectrum caspase inhibitor, to mice with sepsis. We found that Z-VAD-FMK–…
in severe sepsis, and suppressed apoptosis in the spleen and thymus. In vitro, apoptotic cells …
in severe sepsis, and suppressed apoptosis in the spleen and thymus. In vitro, apoptotic cells …
Regulation of human neutrophil apoptosis and lifespan in health and disease
JM McCracken, LAH Allen - Journal of cell death, 2014 - journals.sagepub.com
… molecular mechanisms of neutrophil apoptosis with a focus on … to transiently delay apoptosis
during neutrophil extravasation is … in neutrophil apoptosis during infection and inflammation. …
during neutrophil extravasation is … in neutrophil apoptosis during infection and inflammation. …
Apoptosis and the Resolution of Inflammation in Sepsis
GJ Bellingan - The Sepsis Text, 2002 - Springer
… neutrophil apoptosis can promote inflammatory resolution for example IL-10, which is known
to augment neutrophil apoptosis, … that delayed neutrophil apoptosis could exacerbate or …
to augment neutrophil apoptosis, … that delayed neutrophil apoptosis could exacerbate or …
Molecular biology of inflammation and sepsis: a primer
I Cinel, SM Opal - Critical care medicine, 2009 - journals.lww.com
… of neutrophils in sepsis can potentially contribute to cell/organ injury. Importantly, the
phagocytosis of bacteria and fungi accelerates neutrophil apoptosis. Apoptotic cell clearance …
phagocytosis of bacteria and fungi accelerates neutrophil apoptosis. Apoptotic cell clearance …