T cells are potent early mediators of the host response to sepsis
KR Kasten, J Tschöp, SG Adediran, DA Hildeman… - Shock, 2010 - journals.lww.com
… The degree of circulating lymphocyte apoptosis has been positively correlated with sepsis …
on macrophage and neutrophil function mediated through lymphocyte apoptosis, direct effects …
on macrophage and neutrophil function mediated through lymphocyte apoptosis, direct effects …
[HTML][HTML] Upregulation of the pro-apoptotic genes BID and FAS in septic shock patients
F Turrel-Davin, C Guignant, A Lepape, B Mougin… - Critical Care, 2010 - Springer
… In particular, an increased leukocyte apoptosis has been observed in septic patients [5].
Two major apoptotic pathways are activated: the extrinsic or death receptor-initiated caspase-8 …
Two major apoptotic pathways are activated: the extrinsic or death receptor-initiated caspase-8 …
[HTML][HTML] Decrease of CD4-lymphocytes and apoptosis of CD14-monocytes are characteristic alterations in sepsis caused by ventilator-associated pneumonia: results …
A Pelekanou, I Tsangaris, A Kotsaki, V Karagianni… - Critical care, 2009 - Springer
… with VAP-related sepsis than with sepsis due to other infections. Apoptosis of monocytes
was … was made in patients with temperature above 38C or below 36C, leukocytosis (WBC >…
was … was made in patients with temperature above 38C or below 36C, leukocytosis (WBC >…
Upregulated PD-L1 delays human neutrophil apoptosis and promotes lung injury in an experimental mouse model of sepsis
J Wang, Y Wang, J Xie, Z Zhao, S Gupta… - Blood, The Journal …, 2021 - ashpublications.org
… with sepsis-induced immunosuppression. Other work has shown that neutrophil apoptosis
is … We therefore sought to investigate whether PD-L1 delays ex vivo neutrophil apoptosis by …
is … We therefore sought to investigate whether PD-L1 delays ex vivo neutrophil apoptosis by …
Neutrophil activation during septic shock
L Stiel, F Meziani, J Helms - Shock, 2018 - journals.lww.com
… to the site of infection by chemotaxis or directed migration of leukocytes by means of various
… is therefore associated with increased lymphocytic apoptosis (B and T cells). This apoptosis …
… is therefore associated with increased lymphocytic apoptosis (B and T cells). This apoptosis …
Apoptosis: mechanisms and clinical implications
PCA Kam, NI Ferch - Anaesthesia, 2000 - Wiley Online Library
… In a murine model of septic shock, direct application of TNF-α caused apoptosis in …
decreased neutrophil apoptosis, possibly due to circulating pro-inflammatory anti-apoptotic factors …
decreased neutrophil apoptosis, possibly due to circulating pro-inflammatory anti-apoptotic factors …
Deletion of MyD88 markedly attenuates sepsis-induced T and B lymphocyte apoptosis but worsens survival
OM Peck-Palmer, J Unsinger, KC Chang… - Journal of Leucocyte …, 2008 - academic.oup.com
… ameliorated T and B lymphocyte sepsis-induced apoptosis (∼80% and … sepsis-induced
apoptosis, MyD88 −/− mice had a worsened survival. In conclusion, lymphocyte death in sepsis …
apoptosis, MyD88 −/− mice had a worsened survival. In conclusion, lymphocyte death in sepsis …
[HTML][HTML] Inflammation and cell death of the innate and adaptive immune system during sepsis
C Nedeva - Biomolecules, 2021 - mdpi.com
… Additionally, reduced expression of human leukocyte antigen, HLA-DR, is associated with
… Most importantly, the increase in apoptosis of NK cells during sepsis leads to a decrease in …
… Most importantly, the increase in apoptosis of NK cells during sepsis leads to a decrease in …
Renal cell apoptosis and new treatment options in sepsis-induced acute kidney injury
A Koçkara, M Kayataş - Renal failure, 2013 - Taylor & Francis
… , leukocyte infiltration in glomeruli, interstitial capillaries, and tubular lumen, and apoptosis
in tubular and rarely in glomerular cells. Thrombotic findings were rarely seen. Acute tubular …
in tubular and rarely in glomerular cells. Thrombotic findings were rarely seen. Acute tubular …
Apoptosis markers soluble Fas (sFas), Fas Ligand (FasL) and sFas/FasL ratio in patients with bacteremia: a prospective cohort study
R Huttunen, J Syrjänen, R Vuento, J Laine, M Hurme… - Journal of Infection, 2012 - Elsevier
… apoptosis on a routine basis in septic patients has proved challenging. We here studied the
prognostic value of apoptosis … leukocyte counts and plasma CRP are presented in Table 3. …
prognostic value of apoptosis … leukocyte counts and plasma CRP are presented in Table 3. …