… of sepsis but also in immunology as a whole. In this article, we aimed to review TLR expression
and signaling in the context of sepsis… of new tools to evaluate complex responses, that is, …

… To investigate whether the absence of the receptors of innate immunity contributes to the
local inflammatory response in sepsis through the migration of neutrophils to the peritoneal …

… Toll-Like Receptor 4 (TLR4) signal pathway plays an important role in initiating the innate
immune response and its activation by bacterial endotoxin is responsible for chronic and acute …

… of systemic inflammatory response syndrome/sepsis was … and counterinflammatory responses
during sepsis. Moreover, … include the discovery of TLR4 as the lipopolysaccharide (LPS) …

… to the host response to polymicrobial sepsis, we generated strains of mice with TLR4 deleted
… C3H/HeJ mice express full-length TLR4, but they exhibit defective TLR4 signaling as the …

… the cytokine response to LPS. Therefore, our results show that hyaluronan acts … TLR4, CD44
and A20 to stimulate a unique cellular response that can protect against the septic response …

… of TLR4 signaling and septic shock responses. For TLR4‐mediated IFN induction and septic
shock response, both TRIF‐mediated signaling and intracellular EGFR kinase activity are …

… In particular, TLR4 is part of a recognition complex for … in the inflammatory response to
bacterial sepsis. This review … –TLR4 signaling in the true in vivo picture of bacterial sepsis, …

… on other signaling pathways. We and others have observed such an effect of TLR5 on
TLR4-dependent signaling (Dickey AK, West TE, paper presented at the 2013 American Thoracic …

… for sepsis-associated ARDS. On this regard, this study aims to investigate the role of
TLR4/MyD88 signaling pathway in sepsis-… macrophage activation and inflammatory response. …