Simultaneous determination of ethylene glycol and its major toxic metabolite, glycolic acid, in serum by gas chromatography

HH Yao, WH Porter - Clinical chemistry, 1996 - academic.oup.com
… in serum by packedor capillary-column gas chromatography. Clin Chem 1995;41: 300-5. …
Improved high-performance liquid chromatographic determination of urinary glycolic acid. …

Simultaneous determination of ethylene glycol and glycolic acid in serum by gas chromatography-mass spectrometry

WH Porter, PW Rutter… - Journal of analytical …, 1999 - academic.oup.com
… We describe a gas chromatographic-mass spectrometric (GC-MS) procedure for the … glycolic
acid (GA), in serum. In this method, serum (50 pL) is treated with 150 pt of glacial acetic acid/…

Colorimetric and gas chromatographic procedures for glycolic acid in serum: the major toxic metabolite of ethylene glycol

AD Fraser, W Macneil - Journal of Toxicology: Clinical Toxicology, 1993 - Taylor & Francis
serum. The objective of this procedure was to validate a colorimetric and gas chromatographic
procedure for glycolic acid in serum… and has been shown to be specific for glycolic acid. A …

Analysis of γ-hydroxybutyric acid, DL-lactic acid, glycolic acid, ethylene glycol and other glycols in body fluids by a direct injection gas chromatography-mass …

P Van Hee, H Neels, M De Doncker… - Clinical Chemistry and …, 2004 - degruyter.com
… glycol, glycolic acid, g-hydroxybutyric acid and racemic lactic acid. Only 20 ml of serum, …
After centrifugation an aliquot is transferred to a gas chromatographic system and analyzed …

Simultaneous and cost-effective determination of ethylene glycol and glycolic acid in human serum and urine for emergency toxicology by GC-MS

T Hložek, M Bursová, R Čabala - Clinical Biochemistry, 2015 - Elsevier
… derivatization of glycolic acid with isobutyl chloroformate was achieved directly in serum/urine …
GC-MS analyses were performed using a GC 17A gas chromatograph equipped with AOC-…

Fast determination of ethylene glycol, 1, 2-propylene glycol and glycolic acid in blood serum and urine for emergency and clinical toxicology by GC-FID

T Hložek, M Bursová, R Čabala - Talanta, 2014 - Elsevier
… , and fast gas chromatography method with flame ionization detection (GC-FID) for simultaneous
measurement of ethylene glycol, 1,2-propylene glycol and glycolic acid was developed …

Importance of glycolic acid analysis in ethylene glycol poisoning

AD Fraser - Clinical chemistry, 1998 - academic.oup.com
… Colorimetric and gas chromatographic procedures for glycolic acid in serum: the major toxic
glycolic acid measurements can be useful as a supplement, but not as a substitute, to serum

… glycol (antifreeze) intoxication in dogs by determination of glycolic acid in serum and urine with high pressure liquid chromatography and gas chromatography-mass …

TP Hewlett, AC Ray, JC Reagor - Journal of the Association of …, 1983 - academic.oup.com
… detecting glycolic acid in urine and serum samples. Chemical derivatization of glycolic acid
… comparing serum glycolic acid concentrations in a treated vs a nontreated intoxicated dog. …

Ethylene glycol and glycolic acid in postmortem blood from fatal poisonings

TG Rosano, TA Swift, CJ Kranick… - Journal of analytical …, 2009 - academic.oup.com
… EG and glycolic acid (GA) quantification in postmortem blood by gas chromatography coupled
… and its major toxic metabolite, glycolic acid, in serum by gas chromatography. Clin. Chem. …

Ethylene glycol toxicity: the role of serum glycolic acid in hemodialysis

WH Porter, PW Rutter, BA Bush… - Journal of Toxicology …, 2001 - Taylor & Francis
… glycol poisoning and to determine if glycolic acid levels are predictive of renal failure and …
Methods: We measured serum ethylene glycol and glycolic acid levels by gas chromatography/…