Choice of reference serum creatinine in defining acute kidney injury

ED Siew, ME Matheny - Nephron, 2015 - karger.com
… of acute kidney injury (… creatinine value to anchor the change in serum creatinine used to
determine criteria fulfillment. Ideally, the value chosen accurately reflects steady-state kidney

Performance of serum creatinine and kidney injury biomarkers for diagnosing histologic acute tubular injury

DG Moledina, IE Hall, H Thiessen-Philbrook… - … Journal of Kidney …, 2017 - Elsevier
… of kidney injury would have improved discrimination for diagnosing histologic acute tubular
injury … In a prospective multicenter cohort of deceased organ donors with kidney biopsies …

Marking renal injury: can we move beyond serum creatinine?

JL Slocum, M Heung, S Pennathur - Translational Research, 2012 - Elsevier
… , the Acute Kidney Injury Network (AKIN) criteria, 3 use serum creatinine (SCr) and urine
output to define AKI, leaving SCr as the gold standard determiner of kidney injury for …

Reduced production of creatinine limits its use as marker of kidney injury in sepsis

K Doi, PST Yuen, C Eisner, X Hu… - Journal of the …, 2009 - journals.lww.com
creatinine lag behind both renal injury and recovery. The risk for mortality increases when
acute kidney injury … sought to explore the limitations of serum creatinine in this setting. In mice, …

Creatinine kinetics and the definition of acute kidney injury

SS Waikar, JV Bonventre - Journal of the American Society of …, 2009 - journals.lww.com
… percentage increases in serum creatinine (SCr) over baseline. The Acute Kidney Injury
Network defines the … We simulated creatinine kinetics after AKI in the setting of normal baseline …

Phenotyping of acute kidney injury: beyond serum creatinine

DG Moledina, CR Parikh - Seminars in nephrology, 2018 - Elsevier
kidney injury, and in patients with a structural kidney injury it … or 50% increase in serum
creatinine concentration, which is … examination indicates structural kidney injury, reflects poor …

Creatinine as the gold standard for kidney injury biomarker studies?

SS Waikar, RA Betensky… - Nephrology Dialysis …, 2009 - academic.oup.com
… Unfortunately, however, we face a challenge not faced by cardiologists and pulmonologists:
the uncertain relationship between our ‘gold standard’ biomarkers [serum creatinine (SCr) …

Acute kidney injury

R Bellomo, JA Kellum, C Ronco - The Lancet, 2012 - thelancet.com
… The term also suggests a continuum of prognosis, with increasing mortality associated
with even small rises in serum creatinine, and additional increases in mortality as creatinine

[HTML][HTML] Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury

…, DG Warnock, A Levin, Acute Kidney Injury Network - Critical care, 2007 - Springer
… in serum creatinine or urine output. A staging system for AKI which reflects quantitative changes
in serum creatinine … or AKI based on serum creatinine changes, absolute levels of serum

[HTML][HTML] Acute kidney injury based on KDIGO (Kidney Disease Improving Global Outcomes) criteria in patients with elevated baseline serum creatinine undergoing …

MN Machado, MA Nakazone, LN Maia - Brazilian Journal of …, 2014 - SciELO Brasil
… to apply the Kidney Disease Improving Global Outcomes classification for acute kidney
injury in a population of patients with preoperatively elevated serum creatinine who underwent …