Serum GFAP and UCH-L1 for prediction of absence of intracranial injuries on head CT (ALERT-TBI): a multicentre observational study
JJ Bazarian, P Biberthaler, RD Welch… - The Lancet …, 2018 - thelancet.com
… , non-penetrating TBI and a Glasgow Coma … GFAP were measured in serum and analysed
using prespecified cutoff values of 327 pg/mL and 22 pg/mL, respectively. UCH-L1 and GFAP …
using prespecified cutoff values of 327 pg/mL and 22 pg/mL, respectively. UCH-L1 and GFAP …
ALERT-TBI study on biomarkers for TBI: has science suffered?
AIR Maas, HF Lingsma - The Lancet Neurology, 2018 - thelancet.com
… Serum GFAP and UCH1-L1 in prediction of absence of intracranial injuries on head CT (ALERT-TBI…
test] as an aid in the evaluation of suspected traumatic brain injury (Glasgow Coma …
test] as an aid in the evaluation of suspected traumatic brain injury (Glasgow Coma …
Blood biomarkers on admission in acute traumatic brain injury: relations to severity, CT findings and care path in the CENTER-TBI study
… Our results support the further development of serum GFAP assays towards implementation
… Absolute GFAP levels in our study were much higher than those reported in the ALERT-TBI …
… Absolute GFAP levels in our study were much higher than those reported in the ALERT-TBI …
Comparing glial fibrillary acidic protein (GFAP) in serum and plasma following mild traumatic brain injury in older adults
… We hypothesized that plasma and serum GFAP levels would (i) be highly correlated, (ii)
have similar ability to discriminate between those with and without acute traumatic intracranial …
have similar ability to discriminate between those with and without acute traumatic intracranial …
… value of day-of-injury plasma GFAP and UCH-L1 concentrations for predicting functional recovery after traumatic brain injury in patients from the US TRACK-TBI …
… Furthermore, in patients presenting with traumatic brain injury and a GCS score of 3–12,
incorporating GFAP and UCH-L1 values into the IMPACT models significantly increases the …
incorporating GFAP and UCH-L1 values into the IMPACT models significantly increases the …
Predictive performance of traumatic brain injury biomarkers in high-risk elderly patients
MD Ward, A Weber, VRD Merrill… - The journal of …, 2020 - academic.oup.com
… We also noted significantly higher serum UCH-L1 and GFAP values among elderly patients
… The main ALERT-TBI study was not designed to examine only those ≥65 years of age and …
… The main ALERT-TBI study was not designed to examine only those ≥65 years of age and …
Diagnostic accuracy of prehospital serum S100B and GFAP in patients with mild traumatic brain injury: a prospective observational multicenter cohort study–“the …
SC Seidenfaden, JL Kjerulff, N Juul… - Scandinavian journal of …, 2021 - Springer
… Serum GFAP concentration was measured after one freeze-thaw cycle using a commercial
Human GFAP enzyme-linked immunosorbent assay (ELISA), according to the manufacturer’s …
Human GFAP enzyme-linked immunosorbent assay (ELISA), according to the manufacturer’s …
Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury
EB Button, WH Cheng, C Barron, H Cheung… - Alzheimer's Research & …, 2021 - Springer
… Many other studies have supported these findings using various assays and analytical
platforms [5,6,7] and show that post-TBI serum and plasma GFAP levels can predict magnetic …
platforms [5,6,7] and show that post-TBI serum and plasma GFAP levels can predict magnetic …
Early GFAP and UCH-L1 point-of-care biomarker measurements for the prediction of traumatic brain injury and progression in patients with polytrauma and …
JL Sperry, JF Luther, DO Okonkwo, LE Vincent… - Journal of …, 2024 - thejns.org
… Serum GFAP and UCH-L1 for prediction of absence of intracranial injuries on head CT (ALERT-TBI):
a multicentre observational study. Lancet Neurol. 2018; 17(9): 782-789. …
a multicentre observational study. Lancet Neurol. 2018; 17(9): 782-789. …
… and diagnostic accuracy of glial and neuronal blood biomarkers GFAP and UCH-L1 in a large cohort of trauma patients with and without mild traumatic brain injury
L Papa, GM Brophy, RD Welch, LM Lewis… - JAMA …, 2016 - jamanetwork.com
… TBI. This study evaluated the temporal profiles of serum glial and neuronal serum biomarkers
GFAP … (ED) with and without mild to moderate TBI (MMTBI) and assessed their diagnostic …
GFAP … (ED) with and without mild to moderate TBI (MMTBI) and assessed their diagnostic …
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