… with the correlation of early clearance of serum HE4 combined with CA125 during first-line
treatment … The aim of this study is to evaluate the role of early clearance of HE4 and CA125 in …

… , HE4 levels were lower during the first two … Ca125 levels were higher in the first trimester
compared to nonpregnant women. Creatinine clearance had no effect on Ca125 or HE4 levels. …

… The serum biomarker CA125 was first discovered in 1982 as a … to gain US FDA clearance
for CA125, serum HE4 levels were … basis for the US FDA clearance of HE4 as a biomarker for …

… ELIMination rate constant K value, defined as the CA-125 clearance during the first 100
days of chemotherapy in retrospective studies, represents a good prognostic factor of …

… CA-125 alone, 1 was detected first by CA-125, 5 were revealed only by HE4, 2 were detected
first by HE4 and then by CA-125 … of macroscopic tumor clearance (at an HE4 cutoff value of …

… comparing HE4 and CA 125 performance demonstrated that HE4 is a … early compared with
CA 125. A percentage of elevated HE4 levels were detected already in patients within the first …

… Serum CA125, HE4, and CT images were recorded during … In this study, we first aimed to
evaluate serum HE4 changes … (creatinine clearance G60 mL/min and/or serum creatinine 92.0 …

… in sensitivity when combined with CA125 or other markers 8. In … the sale and use of ROMA
combined HE4 and CA125 in … of HE4 is small, so that it can be secreted into the blood early …

… total macroscopic tumor clearance. Moreover, together with ascites, … of HE4 and CA125 in
the prediction of platinum response during first-line chemotherapy in EOC, reporting that HE4 …

… [16], and as the half time clearance is less than 4 hours [17], … Prognostic value of serum and
tissue HE4 expression in ovarian … HE4: a new potential early biomarker for the recurrence of …