Serum HE4 and CA125 as predictors of response and outcome during neoadjuvant chemotherapy of advanced high-grade serous ovarian cancer

T Vallius, J Hynninen, A Auranen, O Carpén… - Tumor Biology, 2014 - Springer
… after neoadjuvant chemotherapy (NACT) are still under investigation. The aim of this study
was to compare CA125 and HE4Serum HE4 and CA125 samples were taken at the time of …

The role of HE4, a novel biomarker, in predicting optimal cytoreduction after neoadjuvant chemotherapy in advanced ovarian cancer

F Plotti, G Scaletta, S Capriglione, R Montera… - International Journal of …, 2017 - ijgc.bmj.com
… In this study, we first aimed to evaluate serum HE4 changes during NACT and to find a
predebulking surgery cutoff value that is able to predict complete cytoreduction. The secondary …

HE4 as a predictor of adjuvant chemotherapy resistance and survival in patients with epithelial ovarian cancer

M Aarenstrup Karlsen, C Høgdall, L Nedergaard… - Apmis, 2016 - Wiley Online Library
… of serum human epididymis protein 4 (HE4) and HE4 tissue protein expression to predict
tumor resistance to adjuvant chemotherapy, … impossible, neoadjuvant chemotherapy (NACT) …

[HTML][HTML] Kinetics of HE4 and CA125 as prognosis biomarkers during neoadjuvant chemotherapy in advanced epithelial ovarian cancer

JA Alegría-Baños, JC Jiménez-López… - Journal of Ovarian …, 2021 - Springer
Serum HE4 levels were independently associated with TR among patients with AOEC
treated with NACT, also a reduction between baseline HE4 and first chemotherapy levels was …

Serum HE4 profile during primary chemotherapy of epithelial ovarian cancer

J Hynninen, A Auranen, K Dean, M Lavonius… - International Journal of …, 2011 - ijgc.bmj.com
… In the neoadjuvant chemotherapy group, HE4 correlated better with the radiologic response
… of serum HE4 changes could improve the evaluation of response to chemotherapy in …

Serum HE4 superior to CA125 in predicting poorer surgical outcome of epithelial ovarian cancer

Y Shen, L Li - Tumor Biology, 2016 - Springer
… ) of HE4 before and after neoadjuvant chemotherapy could predict optimal interval debulking
surgery. Serum HE4 … or percentage) of HE4 in neoadjuvant chemotherapy could predict the …

[HTML][HTML] Could HE4 level measurements during first-line chemotherapy predict response to treatment among ovarian cancer patients?

A Chudecka-Głaz, A Cymbaluk-Płoska, M Wężowska… - PloS one, 2018 - journals.plos.org
… treatment and 42 patients qualified for neoadjuvant chemotherapy. Each patient underwent
… A univariate logistic regression analysis showed that serum HE4 significantly correlated with …

[HTML][HTML] Serum CA125 and HE4 levels as predictors for optimal interval surgery and platinum sensitivity after neoadjuvant platinum-based chemotherapy in patients …

A Pelissier, A Roulot, B Guéry, C Bonneau… - Journal of ovarian …, 2016 - Springer
Serum HE4 is more specific than CA125 in discriminating … In addition to its diagnostic value,
the serum HE4 level may be … profile of the HE4 level during neoadjuvant chemotherapy (NAC…

[HTML][HTML] Serum HE4, CA125, YKL-40, bcl-2, cathepsin-L and prediction optimal debulking surgery, response to chemotherapy in ovarian cancer

AM Chudecka-Głaz, AA Cymbaluk-Płoska… - Journal of ovarian …, 2014 - Springer
… In our study, the mean value of HE4 in the group of patients radically operated at the moment
of diagnosis was 78.87 pmol/L and in the group treated with neoadjuvant chemotherapy

[HTML][HTML] Role of serum HE4 as a prognostic marker in carcinoma of the ovary

M Lakshmanan, V Kumar, A Chaturvedi… - Indian Journal of …, 2019 - journals.lww.com
… We evaluated serum CA125 and serum HE4 response after treatment completion in both …
and after neoadjuvant chemotherapy in the IDS group. We found that a >80% fall in serum HE4