… Hyperuricemia is a key causal factor for gout 7 , and all patients with gout are expected to …
for gout in clinical practice as well as clinical trials have focused on lowering serum uric acid (…

… Gout is a progressive, painful, debilitating form of inflammatory arthritis. It is caused by factors
that elevate the concentration of serum uric acid … The prevalence of hyperuricemia and gout …

… The relation between gout and uric acid is such that in general … gout in the presence of
hyperuricaemia. Conversely the diagnosis of gout may be rejected when a normal serum uric acid …

… of gout attacks was also seen in a study of men with gout who were given ULT (allopurinol or
allopurinol … between average serum uric acid level and the incidence of acute gouty arthritis …

… The heritability of serum uric acid levels has been estimated to be ∼40% 10,11 , consistent
… and both serum uric acid levels and gout. A total of 789 Icelandic individuals with gout have …

… Serum uric acid determinations were made for 6,000 study subjects from the Tecumseh …
hyperuricemia or gout. Male subjects, of whom there were 2,987, had serum uric acid values …

… attention to a relationship which must be considered when examining the role of serum uric
acid and serum glucose, diabetes and gout, in the development of ischaemic heart disease. …

… Allopurinol decreases serum uric acid levels by inhibiting the enzyme xanthine oxidase. We
hypothesized that administrating allopurinol to decrease serum uric acid … with allopurinol, …

… of modeling, baseline gout and the interaction of baseline gout with uric acid were added to
… on baseline uric acid alone. In the final stage of modeling, the diagnosis of gout history at …

… In this Review, we describe the associations between common genetic variants, serum
uric acid levels and gout as well as the role of these variants in hyperuricaemia and …