An updated review of genetic associations with severe adverse drug reactions: Translation and implementation of pharmacogenomic testing in clinical practice

CW Wang, IAC Preclaro, WH Lin… - Frontiers in …, 2022 - frontiersin.org
… Skin injury is classified from mild maculopapular exanthema (MPE) to life-threatening severe
cutaneous adverse drug reactions (SCAR), including drug reactions with eosinophilia and …

Predicting risk of adverse drug reactions in older adults

AH Lavan, P Gallagher - Therapeutic advances in drug …, 2016 - journals.sagepub.com
… has sufficient predictive value for clinical practice. Good clinical practice for detecting and …
Serum albumin levels are often reduced by chronic illness, malnutrition and dietary changes…

Adverse drug reactions in special populations–the elderly

EA Davies, MS O'mahony - British journal of clinical …, 2015 - Wiley Online Library
… and greater vulnerability to adverse drug reactions (ADRs). Medical practice is often based
on … In total, 39% of all adverse events were categorized as serious or possibly life threatening; …

Clinical and economic burden of adverse drug reactions

J Sultana, P Cutroneo, G Trifirò - Journal of Pharmacology …, 2013 - journals.sagepub.com
Adverse drug reactions (ADRs) are unwanted drug effects that have considerable economic
as well as clinical … to inappropriate medication use occur often in the real world of clinical

Severe adverse drug reactions of antidepressants: results of the German multicenter drug surveillance program AMSP

D Degner, R Grohmann, S Kropp, E Rüther… - …, 2004 - thieme-connect.com
… The goal of the German drug safety program in psychiatry AMSP (Arzneimittelsicherheit in
der Psychiatrie) is the assessment of severe or new adverse drug reactions (ADRs). Here we …

[HTML][HTML] Factors affecting the development of adverse drug reactions

MJ Alomar - Saudi pharmaceutical journal, 2014 - Elsevier
… Eighteen percent of drugs related to ADRs in the Harvard medical practice study were judged
… the same time for different diseases or acute or chronic conditions. ADRs may occur due to …

Severe cutaneous adverse drug reactions: presentation, risk factors, and management

SS Mustafa, D Ostrov, D Yerly - Current allergy and asthma reports, 2018 - Springer
adverse drug reactions occur commonly in clinical practice … , and severe cutaneous
adverse drug reactions (SCAR). … T cell-mediated reaction. The spectrum of illness ranges from …

Pirfenidone and nintedanib for pulmonary fibrosis in clinical practice: tolerability and adverse drug reactions

JA Galli, A Pandya, M Vega‐Olivo, C Dass… - …, 2017 - Wiley Online Library
clinical practice had drug tolerability and adverse event profiles comparable with
subjects enrolled in clinical … discontinuation rate similar across all stages of IPF severity (22.9–26.7%).…

Adverse drug reactions: definitions, diagnosis, and management

IR Edwards, JK Aronson - The lancet, 2000 - thelancet.com
… Rapid action is sometimes important because of the serious nature of a suspected adverse
drug reaction, for example anaphylactic shock. Emergency treatment and withdrawal of all …

Exploring healthcare professionals' practices and attitudes towards monitoring and reporting of severe adverse drug reactions

W Srisuriyachanchai, AR Cox, N Jarernsiripornkul - Healthcare, 2022 - mdpi.com
… Healthcare professionals (HCPs) play a key role in the monitoring of severe adverse drug
reactions (ADRs). The present study aims to explore practices and barriers of HCPs in severe