… The incorporation of measures of health care utilization and medication use into the definition
of severe asthma is crucial to allow investigators and clinicians to identify the patients at …

… asthma of a minority remains only partially controlled, or even uncontrolled, despite intensive
treatment. This asthma, termed severe asthma, … the majority of medical resource use (6, 7). …

… opportunities to describe use of biologics for treating severe asthma in current clinical …
patterns of biologic use (continuation, switches, and discontinuations) for severe asthma, elucidate …

… has been the improvement in our understanding of the underlying pathophysiology, which
resulted in the development and commercialization of new medications and to a better use of …

… ) represents an advance in the treatment of severe allergic asthma when symptoms remain
despite use of optimum combination treatment. In a series of six phase III clinical trials in …

… of severe asthma in a large adult population-based asthma cohort followed for 10-28 years,
based on severe asthma … of shortness of breath, or asthma medication use last 12 months. …

… severe asthmatics in a clinical setting, particularly since they did not include therapy in defining
asthma … The association between recreational drug use and asthma has been reviewed …

… We sought to evaluate the risk of SCS-related complications by SCS exposure and
quantify the associated health care costs and resource use in patients with severe asthma. …

… 3 summarizes, within the limitations of existing label information at the time of writing this
paper, the attributes of the biologics currently licensed for use in patients with severe asthma. …

… Meta-analyses have shown that there is insufficient evidence to support the use of these
drugs in the routine treatment of severe asthma as steriod-sparing agents. In most cases, the …