… All consecutive patients with a diagnosis of severe sepsis or septic shock, in whom … on
a more severe population of patients, suffering from severe sepsis and septic shock, with …

… of critically ill patients with severe sepsis, we aimed to compare … versus intermittent infusion
of β-lactam antibiotics. … of β-lactam antibiotics in critically ill patients with severe sepsis. We …

… infusion in patients with severe sepsis. The aim of the β-Lactam Infusion Group (BLING) II …
and intermittent β-lactam antibiotic infusion in patients with severe sepsis in alive intensive …

… The BLISS study was a prospective, two-centre, open-labelled RCT of CI versus IB dosing
of beta-lactam antibiotics in critically ill patients with severe sepsis from the two following …

… optimal dosing of beta-lactam antibiotics has the potential to improve the outcome for critically
ill patients with severe sepsis. Beta-lactam antibiotics are administered almost exclusively …

… Severe infection was defined as clinical evidence of infection… the same β lactam from studies
that compared different β lactams. … infection, bacteraemia, and specific sources of infection. …

… prolonged β-lactam infusion strategy has emerged as the standard treatment for sepsis or
septic … versus intermittent β-lactam antibiotics infusion on outcomes in sepsis or septic shock …

… in the literature concerning sepsis or septic shock due to … peculiar clinical characteristics of
sepsis or septic shock due to … of outcome in septic patients with severe sepsis or septic shock …

… With its increasing incidence [2] and with mortality rates up to 82% for severe sepsis and
septic … β-lactam antibiotics are commonly selected as empirical therapy for severe infections in …

… Severe sepsis or septic shock alters the β-lactam PK principally through increases in … The
best relevant parameter indicating β-lactam efficacy is the time plasma antibiotic levels remain …