… which we did not detect FOXP2 expression, including the developing … FOXP2 expression
is refined to specific substructures within positive regions. For example, early diffuse expression …

… Moreover, the striking conservation of both FoxP2 sequence and neural expression in …
mutation (R328X) predicted to severely truncate the FOXP2 protein. Although there was no …

… She works closely with the coauthors of this review both in identifying genes that cause severe
speech disorder and in characterizing speech and language in known genetic conditions. …

… also lead to more severe phenotypes in cases where … FOXP2 expression was present in
the proband. We analyzed allele-specific expression of FOXP2 by Sanger sequencing of FOXP2 …

… FOXP2 gene (MIM 605317) has been implicated in a severe … speech and language deficits,
requesting testing for FOXP2 … , patients were selected for FOXP2 screening only if they …

… name of ‘FOXP2’ (see Box 1) results in a severe developmental disorder that significantly
disrupts speech and language skills. The discovery of a link between FOXP2 and spoken …

… Thus the Foxp2/FOXP2 expression pattern in the basal ganglia … aspects in which Foxp2/FoxP2
striatal expression differs in … Localisation of a gene implicated in a severe speech and …

… of FOXP2, thus expected to result in severe loss of function of the protein. Functional studies
confirmed severe impairment of FOXP2 … The views expressed in this publication are those of …

… with a submicroscopic deletion of FOXP2: a boy with severe apraxia of speech and his currently
… 5) and sensorimotor consequences of reduced FOXP2 expression in cortical, cerebellar, …

… Mutations of the FOXP2 gene cause a severe speech and … concordant with sites of high
FOXP2 expression, which include … that FOXP2 impacts on brain areas implicated in speech and …