Increased levels of interleukin-6,-8 and-10 are associated with fatal outcome following severe traumatic brain injury

LCB Ferreira, A Regner, KDL Miotto, S Moura, N Ikuta… - Brain injury, 2014 - Taylor & Francis
… cytokines after severe traumatic brain injury (TBI). Control subjects compared to TBI
patients at three time points after injury. Box plots denote mean with SEM (solid line). Levels of …

Association between cerebrospinal fluid interleukin-6 concentrations and outcome after severe human traumatic brain injury

A Singhal, AJ Baker, GMT Hare, FX Reinders… - Journal of …, 2002 - liebertpub.com
Acute inflammation plays a significant role in the pathophysiology of traumatic brain injury
(TBI). … fluid interleukin-1 (IL-1) and interleukin-6 (IL-6) concentrations in 36 patients, following …

[HTML][HTML] Interleukin-6 as a prognostic biomarker of clinical outcomes after traumatic brain injury: A systematic review

SZY Ooi, RJ Spencer, M Hodgson, S Mehta… - Neurosurgical …, 2022 - Springer
… Table 1 Summary of included studies analysing the prognostic value of interleukin-6
levels in patients with traumatic brain injury after a systematic review of the literature …

Acute CSF interleukin-6 trajectories after TBI: associations with neuroinflammation, polytrauma, and outcome

RG Kumar, ML Diamond, JA Boles, RP Berger… - Brain, behavior, and …, 2015 - Elsevier
… trajectories of acute CSF IL-6. The high group had higher acute CSF and sub-acute serum
Traumatic brain injury (TBI) results in a significant inflammatory burden that perpetuates the …

Raised parenchymal interleukin6 levels correlate with improved outcome after traumatic brain injury

CD Winter, AK Pringle, GF Clough, MK Church - Brain, 2004 - academic.oup.com
interleukin6 (IL‐6) and interleukin‐1β (IL‐1β) can influence patient outcome following a
severe head injury… in CSF or serum, rather than the brain parenchyma itself. Recently, a method …

Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries

T Kossmann, VHJ Hans, HG Imhof, R Stocker, P Grob… - Shock, 1995 - journals.lww.com
severe traumatic brain injury (TBI) show a profound acute-phase response. Because
interleukin-6 (IL-6) is an important mediator of these pathophysiological changes, IL-6 levels were …

Interleukin-6 and nerve growth factor upregulation correlates with improved outcome in children with severe traumatic brain injury

A Chiaretti, A Antonelli, A Mastrangelo… - Journal of …, 2008 - liebertpub.com
6 in injured brain and the lack of studies on NGF expression in patients with traumatic brain
injury… IL-6 and NGF in the CSF of children with severe TBI to determine their relationship with …

Comparison of the interleukin-6 and interleukin-10 response in children after severe traumatic brain injury or septic shock

MJ Bell, PM Kochanek, LA Doughty, JA Carcillo… - Brain Edema X …, 1997 - Springer
… Kossmann T, Hans VHJ, Imhof HG, et af (l995) Intrathecal and serum interleukin-6 and the
acute-phase response ill patients with severe traumatic brain injuries. Shock 4: 311-317 3. …

Interleukin-6 released in human cerebrospinal fluid following traumatic brain injury may trigger nerve growth factor production in astrocytes

T Kossmann, V Hans, HG Imhof, O Trentz… - Brain research, 1996 - Elsevier
… Twenty-two patients with severe brain injury were included in this study. The types of trauma,
intraccrebral injuries, and the initial Glasgow Coma Score (GCS) are given in the table. All …

[HTML][HTML] The relationship between serum levels of interleukins 6, 8, 10 and clinical outcome in patients with severe traumatic brain injury

S Yousefzadeh-Chabok, AD Moghaddam… - Archives of trauma …, 2015 - ncbi.nlm.nih.gov
… Measuring concentrations of interleukin 6, 8 and 10 in blood serum of … 6 months after head
injury based on Glasgow outcome scale (GOS) as death outcome, vegetative state, severe