… Shc family of proteins differed between DRG and PC12 cells. … in DRG neurons and PC12
cells. The predominantly expressed … and 52 kDa proteins whereas those in PC12 cells were the …

… PC12 cells consistently contained a 43-kDa protein that was associated with Shc, a signal-transducing
protein … (GST)-Shc fusion protein, the 43-kDa protein was identified as actin by …

… For EGF-induced mitogen-activated protein kinase activation in 293T cells, both Shc PTB …
engagement with Shc may exist. For NGF-induced neurite outgrowth in PC12 cells, Shc PTB …

… It has also been demonstrated that PC12 cells expressing mutant Shc proteins in which
tyrosine residue 239/240 is substituted by phenylalanine could not undergo neurite outgrowth in …

… Shc proteins, and their associationwith the tyrosine PI-3P phosphorylated receptors in PC-12
cells… lin to activate this pathway in PC-12 cells, we analyzed the tyrosine phosphorylation of …

… To address the question of the potential association of the adaptor proteins FRS2 and
Shc with ALK, we first performed co-immunoprecipitation experiments in HEK 293 …

… These effects could not be explained by altered signaling through the phospholipase C-,
Shc, or FGF receptor substrate-2 (FRS2) pathways or by influences on ERK activation, and it …

… Recently, Rozakis-Adcock et al. reported that the neuronal differentiation of PC12 cells
induced by Shc, an SH2-containing protein, was also inhibited by the dominantnegative mutant …

… Therefore, the possibility that during differentiation of PC12 cells, Shc proteins may interact
… either anti-Shc or anti-PLD1 antibodies. Interestingly, we have found that the Shc proteins (66…

… of Shc with the activated NGF receptor (TrkA), we used parental PC12 cells and PC12 cells
… In these studies, we were not able to use full-length GST-Shc protein since it was rapidly …