Synthesis and Structure–Activity Relationships of Novel Abietane Diterpenoids with Activity against Staphylococcus Aureus

MF Chabán, AI Antoniou, C Karagianni… - Future Medicinal …, 2019 - Taylor & Francis
Synthesis of abietic acids derivatives … General procedure for the synthesis of the oximes
11–17 & 25–28 A mixture of aldehyde 7 or ketones 3, 8, 9, 10, 23, 24 (the synthesis of the …

Stereocontrolled radical bicyclizations of oxygenated precursors enable short syntheses of oxidized abietane diterpenoids

D Vrubliauskas, BM Gross… - Journal of the American …, 2021 - ACS Publications
… , we targeted several C20 oxidized abietane diterpenoids bearing different oxygenation
patterns. Close to 100 aromatic abietane diterpenoids have been reported, and they include …

Aromatic abietane diterpenoids: total syntheses and synthetic studies

MA González - Tetrahedron, 2015 - Elsevier
… Recently, González and Pérez-Guaita reported a short synthesis of ferruginol (3) from
commercially available (+)-dehydroabietylamine (63) (Scheme 11), which is not a natural product …

Abietane Diterpenoids from Clerodendrum bungei

S Liu, H Zhu, S Zhang, X Zhang, Q Yu… - Journal of Natural …, 2008 - ACS Publications
… This has led to the isolation and structure elucidation of five new abietane-type diterpenoids
(1–5) and the purification of three known substances (6–8). Compounds 1–8 were …

Bioinspired synthesis of pygmaeocins and related rearranged abietane diterpenes: Synthesis of viridoquinone

MA El Had, JJ Guardia, JM Ramos, M Taourirte… - Organic …, 2018 - ACS Publications
synthesis of rearranged abietane diterpenes related to pygmaeocins, in which the key step is
the 1,2-migration of the C-20 angular methyl to the C-5 position of the abietanesynthesis of …

Efficient Asymmetric Synthesis of abeo-Abietane-Type Diterpenoids by Using the Intramolecular Heck Reaction

M Node, M Ozeki, L Planas, M Nakano… - The Journal of …, 2010 - ACS Publications
… -abietane-type diterpenes using an intramolecular asymmetric Heck reaction of triflate 6, as
shown in Scheme 1. Herein, we report the first synthesis of … and ee within shorter steps than …

Abietane diterpenoids from Isodon lophanthoides var. graciliflorus and their cytotoxicity

W Zhou, H Xie, P Wu, X Wei - Food chemistry, 2013 - Elsevier
… Seven new (1–7) and three known (8–10) abietane diterpenoids were isolated from the
methanolic extract of the aerial parts of Isodon lophanthoides var. graciliflorus (Lamiaceae), a …

Antiviral profiling of C-18-or C-19-functionalized semisynthetic Abietane diterpenoids

MA González-Cardenete, D Hamulic… - Journal of Natural …, 2022 - ACS Publications
… For the synthesis of compound 6, we optimized the synthesis procedure reported by
Waldvogel and co-workers for compound 6 from ca. 65% (+)-dehydroabietylamine (3) in four …

Increasing the synthesis of bioactive abietane diterpenes in Salvia sclarea hairy roots by elicited transcriptional reprogramming

MC Vaccaro, A Mariaevelina, N Malafronte… - Plant cell reports, 2017 - Springer
… We have shown that aethiopinone, an abietane diterpene … this compound and other abietane
diterpenes, hairy root technology … , significantly higher than the content either after short or …

Anticancer properties of the abietane diterpene 6, 7-dehydroroyleanone obtained by optimized extraction

C Garcia, CO Silva, CM Monteiro, M Nicolai… - Future medicinal …, 2018 - Taylor & Francis
… In this work, the abietane diterpene DHR quantification for all distillates obtained and for
each extraction method was performed by HPLC-DAD (retention time [R t ] DHR = 23.6 min). …