Sickle-cell disease
… Most people with sickle-cell disease live in Africa, where little is known about this disease; …
of the world and that infectious diseases have a role in causing this increased severity of …
of the world and that infectious diseases have a role in causing this increased severity of …
Sickle-cell disease
MJ Stuart, RL Nagel - The Lancet, 2004 - thelancet.com
With the global scope of sickle-cell disease, knowledge of the countless clinical presentations
and treatment of this disorder need to be familiar to generalists, haematologists, internists, …
and treatment of this disorder need to be familiar to generalists, haematologists, internists, …
Sickle cell disease
RE Ware, M de Montalembert, L Tshilolo, MR Abboud - The Lancet, 2017 - thelancet.com
… Pneumococcal conjugate vaccines have dramatically reduced the incidence of invasive
pneumococcal disease in sickle cell disease, but non-vaccine serotypes could emerge. …
pneumococcal disease in sickle cell disease, but non-vaccine serotypes could emerge. …
Cerebrovascular accidents in sickle cell disease: rates and risk factors
…, FM Gill, CS Sickle Cell Disease - Blood, The Journal …, 1998 - ashpublications.org
… of sickle cell disease. The incidence and mortality of and risk factors for CVA in sickle cell
disease … The Cooperative Study of Sickle Cell Disease collected clinical data on 4,082 sickle …
disease … The Cooperative Study of Sickle Cell Disease collected clinical data on 4,082 sickle …
Sickle cell disease
… Sickle cell disease (SCD) is an umbrella term that defines a group of inherited diseases (including
sickle cell anaemia (SCA), HbSC and HbSβ-thalassaemia, see below) characterized …
sickle cell anaemia (SCA), HbSC and HbSβ-thalassaemia, see below) characterized …
Sickle-cell disease
GR Serjeant - The Lancet, 1997 - thelancet.com
Populations informed and educated about the genetics of the disease and about their own
genetic status may elect to avoid relationships between carriers. It may be feasible to …
genetic status may elect to avoid relationships between carriers. It may be feasible to …
Management of sickle cell disease
MH Steinberg - New England Journal of Medicine, 1999 - Mass Medical Soc
… persons with sickle cell disease the erythrocytes … sickle cells, endothelial cells, and
constituents of plasma. Deoxygenation of sickle cells induces potassium efflux, which increases cell …
constituents of plasma. Deoxygenation of sickle cells induces potassium efflux, which increases cell …
Sickle cell disease
Much progress has been made during the past several decades in gaining understanding
about the natural history of sickle cell disease and management approaches aimed at treating …
about the natural history of sickle cell disease and management approaches aimed at treating …
Pathogenesis and treatment of sickle cell disease
HF Bunn - New England Journal of Medicine, 1997 - Mass Medical Soc
… as well as in sickle erythrocytes, 7 have provided critical insights into the pathogenesis of
the vaso-occlusive events that play such an important part in sickle cell disease. In contrast, …
the vaso-occlusive events that play such an important part in sickle cell disease. In contrast, …
Sickle cell disease
LH Pecker, S Lanzkron - Annals of internal medicine, 2021 - acpjournals.org
Sickle cell disease is an umbrella term for a group of hemoglobinopathies characterized by
the presence of 2 β-globin gene mutations or deletions, at least 1 of which is the point …
the presence of 2 β-globin gene mutations or deletions, at least 1 of which is the point …