… In the course of our behavioral screens to identify novel sleep-regulatory genes and
neurons, we found evidence that SIFamide (SIFa)-expressing neurons promote sleep. The SIFa …

… In the current study, we focused on SIFamide (SIFa), a neuropeptide found in the PI. SIFa is
… shown to play a role in diverse behaviors in Drosophila. For example, the ablation of SIFa …

… Here, we investigate the regulation of appetitive and feeding behavior in the fruit fly,
Drosophila melanogaster. We report that four neurons in the fly brain that release SIFamide are …

… and sleep-bout length [17]. Interestingly, SIFaN execute the sleep-promoting function via
SIFamide receptor-… This study describes the role of a set of four SIFamide-producing neurons in …

… of SIFamide receptor expressing neurons necessary for each behaviour and studied the
contribution of circadian clock genes within the SIFamide … Our results show that SIFamide …

… It has already been shown to affect sleep behavior [12], while in … of SIFamide in the fruit
fly seems to be more limited than in other arthropods. For example, in crustaceans SIFamide is …

… Drosophila responds to heat stress with an increase in sleep. In contrast to Drosophila
infection-induced sleep, heat-induced sleep … Moreover, the sleep response to heat stress does not …

… In the brain of Drosophila melanogaster, ~150 circadian clock neurons … SIFamide (SIFa)
contributes to circadian rhythms of feeding. Here, we demonstrate a role for SIFa Receptor (…

… While we cannot directly compare Drosophila sleep stages to the stages of mammalian
sleep, it is now evident that changes in sleep depth are also a feature of invertebrate sleep. …

… Whereas SIFamide is implicated in mating and sleep regulation in Drosophila, other
functions of this … The SIFamide of Drosophila differs only in the first amino acid at the N-terminus. …