Phosphodiesterases in neurodegenerative disorders
E Bollen, J Prickaerts - IUBMB life, 2012 - Wiley Online Library
… age-related neurodegenerative disorder is … signaling pathway has been reported in human
patients with AD (27-29). As a main activator of CREB, a decrease in AC/cAMP/PKA signaling …
patients with AD (27-29). As a main activator of CREB, a decrease in AC/cAMP/PKA signaling …
Apoptosis in neurodegenerative disorders
MP Mattson - Nature reviews Molecular cell biology, 2000 - nature.com
… signal-mediated neuroprotection pathways, several intracellular signalling pathways have
… surface receptor-mediated kinase signalling pathways that ultimately induce expression of …
… surface receptor-mediated kinase signalling pathways that ultimately induce expression of …
The role of PI3K/Akt and ERK in neurodegenerative disorders
… Akt is also involved with PI3K in signaling pathway to mediate neuronal survival. ERK is
another kinase which also regulates proliferation, differentiation, and survival of the neural cell. …
another kinase which also regulates proliferation, differentiation, and survival of the neural cell. …
The molecular bases of Alzheimer's disease and other neurodegenerative disorders
RB Maccioni, JP Muñoz, L Barbeito - Archives of medical research, 2001 - Elsevier
… signaling pathways in neuronal cells, leading to biochemical and structural abnormalities
and neurodegeneration … normal signaling pathways of functional neurons directly involved in …
and neurodegeneration … normal signaling pathways of functional neurons directly involved in …
The Nrf2-ARE Signalling pathway: promising drug target to combat oxidative stress in neurodegenerative disorders
FL van Muiswinkel, HB Kuiperij - … & Neurological Disorders, 2005 - ingentaconnect.com
… events in the pathogenesis of these neurodegenerative disorders, and may therefore provide
… ARE signalling pathway is an attractive therapeutic target for neurodegenerative diseases, …
… ARE signalling pathway is an attractive therapeutic target for neurodegenerative diseases, …
Gene networks in neurodegenerative disorders
D Recabarren, M Alarcon - Life sciences, 2017 - Elsevier
… Calmodulin 1 (Calm1) is a multifunctional calcium ion sensor protein that transduces
calcium signalling pathway, associated with the migration of mouse precerebellar neurons [131]. …
calcium signalling pathway, associated with the migration of mouse precerebellar neurons [131]. …
… as novel therapeutic strategy for neurodegenerative disorders: Antiapoptotic and antiamyloidogenic activities by modulation of cellular signal pathways
M Naoi, M Shamoto-Nagai, W Maruyama - Future Neurology, 2019 - Taylor & Francis
… age-associated neurodegenerative disorders is an oppressive issue for medical care, society
and economy. The etiology of two most common neurodegenerative disorders, Alzheimer's …
and economy. The etiology of two most common neurodegenerative disorders, Alzheimer's …
Role of metabolism in neurodegenerative disorders
C Procaccini, M Santopaolo, D Faicchia, A Colamatteo… - Metabolism, 2016 - Elsevier
… insulin signaling in the pathogenesis of AD [26]. The insulin signaling pathway contributes
… survival; alteration of brain insulin signaling can determine the cognitive deficits observed in …
… survival; alteration of brain insulin signaling can determine the cognitive deficits observed in …
[HTML][HTML] TLR-mediated signal transduction and neurodegenerative disorders
SV Adhikarla, NK Jha, VK Goswami, A Sharma… - Brain sciences, 2021 - mdpi.com
… use of MyD88-independent signaling pathways, using TRIF as an adaptor [16]. TLR4 is only
one of its kind, as it utilizes both MyD88-dependent and MyD88-independent pathways [17]. …
one of its kind, as it utilizes both MyD88-dependent and MyD88-independent pathways [17]. …
[HTML][HTML] NF-κB in neuronal plasticity and neurodegenerative disorders
MP Mattson, S Camandola - The Journal of clinical …, 2001 - Am Soc Clin Investig
… Signaling pathways that regulate NF-κB activity in neurons, and their possible involvement
in the pathogenesis of neurodegenerative disorders. NF-κB in its inactive form is present in …
in the pathogenesis of neurodegenerative disorders. NF-κB in its inactive form is present in …
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