Mechanisms and functions of p38 MAPK signalling

A Cuadrado, AR Nebreda - Biochemical journal, 2010 - portlandpress.com
… underlying p38 MAPK functions, with special emphasis on the activation and regulation
of the core kinases, the interplay with other signalling pathways and the nature of p38 MAPK

MAP kinase pathways activated by stress: the p38 MAPK pathway

T Obata, GE Brown, MB Yaffe - Critical care medicine, 2000 - journals.lww.com
… One can safely assume that similar signaling pathways link PAKs to p38 MAPKp38 MAPK,
the entire signaling pathway from the IL-1 receptor to TAK-1, a MAPKKK for p38 MAPK and …

The p38 MAP kinase pathway and its biological function

L New, J Han - Trends in cardiovascular medicine, 1998 - Elsevier
… Thus, the p38 MAP kinase cascade may consist of the sequence: MEKK5’MKK3/6’p38α/β/γ/δ,
as … is an overlap of these nonreceptor–mediated p38 signal pathways at the initiation step. …

Activation and signaling of the p38 MAP kinase pathway

T Zarubin, J Han - Cell research, 2005 - nature.com
… a senescent phenotype dependent upon p38 MAPK activity. Also, p38 MAPK activity was
shown … Downstream signaling pathways of p38 are quite divergent and each component may …

Signal integration by JNK and p38 MAPK pathways in cancer development

EF Wagner, ÁR Nebreda - Nature Reviews Cancer, 2009 - nature.com
… JNKs and p38 MAPKs can exert antagonistic effects on cell … of the signal and the crosstalk
between other signalling pathways. Crosstalk between the JNK and p38 MAPK pathways is …

p38 MAPK signalling cascades: ancient roles and new functions

E Martín‐Blanco - Bioessays, 2000 - Wiley Online Library
… The p38 (D-p38a/D-p38b) signalling pathway directs the immune response and seems to
be involved in oocyte polarity and cell fate specification in imaginal discs; lic (D-MKK3) has …

[HTML][HTML] p38 MAP-kinases pathway regulation, function and role in human diseases

A Cuenda, S Rousseau - Biochimica et Biophysica Acta (BBA)-Molecular …, 2007 - Elsevier
… by a MAPK kinase kinase (MKKK). The MKKK responsible for activating the p38 MAPK
pathways … Several MKKKs have been implicated in the regulation of p38 MAPK signalling, these …

The p38 MAPK signaling pathway: a major regulator of skeletal muscle development

A Keren, Y Tamir, E Bengal - Molecular and cellular endocrinology, 2006 - Elsevier
… that transmit largely unknown signals into the cell affecting … signaling pathway activated
during the differentiation of myogenic cell lines is p38 mitogen-activated protein kinase (MAPK

The p38 MAP kinase signaling pathway in Alzheimer's disease

GVW Johnson, CDC Bailey - Experimental neurology, 2003 - Elsevier
P38 map kinase activation and function p38 MAP kinases are activated by numerous unique
signals… of the p38 MAP kinase family 19, 42. In neuronal systems many stimuli that increase …

Novel strategies for inhibition of the p38 MAPK pathway

J Zhang, B Shen, A Lin - Trends in pharmacological sciences, 2007 - cell.com
… , including non-ATP-competitive inhibitors and inhibitors that are targeted to other components
of the signaling pathway. … Activation and signaling of the p38 MAP kinase pathway. …