… molecules control their specificity to given effectors by … signal specificity of a given regulatory
device depends not only on the TF involved but also on TF connectivity to upstream signals …

… The presence of so many highly related signaling proteins in … the similarity between signaling
proteins to integrate signals or … dictate the specificity of two-component signaling pathways. …

… This regulatory device causes a premature response to a signal (3MBz) that will appear in the
system … Regulator and enzyme specificities of the TOL plasmid-encoded upper pathway for …

… of TLR signaling pathway in animals at network-level. Our results showed that the nucleotide
substitution rate was negatively correlated with gene position along TLR signaling pathway …

… Eukaryotic cells control signal transduction by compartmentalizing membrane surfaces
so that signaling reactions are registered with high spatial and temporal precision. …

… some additional wiring of the TOL network for entering other physiological signals. In fact, a
… wiring between the global and the TOL-specific expression networks. Not surprisingly, these …

… TOL-1 does not initiate the NF-κB-dependent signaling pathways (53, 57). Although previous
studies have shown that TOL… elegans, the downstream pathways activated by TOL-1 during …

… functionality of predicted TOL UBDs, which appear to exhibit binding specificities similar
to … Moreover, a preferential signal of PIN2:ubq:VENUS at the PM in tolQ implies TOL …

… Although the conserved signaling core of this network is well characterized, ligand specificities
… We subsequently mapped specificities of these ligands by performing Förster resonance …

… on how bacteriocins like colicins exploit the Tol (or more commonly Tol-Pal) system to kill …
on Tol-Pal function in Gram-negative bacteria. What emerges from these studies is that Tol-Pal …