… STAT4 is a member of the signal transducer and activator of transcription (STAT) family of …
liver of several mouse models of liver injury, as well as the human liver of chronic liver diseases…

… liver injury models. In this review, we highlight recent advances in STAT3 signaling in liver
… and discuss the potential application of STAT3 as a therapeutic target to treat liver diseases. …

… liver inflammation, steatosis, and hepatocellular damage in alcoholic and nonalcoholic fatty
liver disease … Compared with wild-type mice, IL-10 2/2 mice had greater liver inflammatory …

… Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in
affluent countries. Recent studies have reported that circular RNAs (circRNAs) are important …

… upregulation of the NF-κB signaling pathway and subsequently enhances expression of …
liver. Downregulation of the antiapoptotic STAT3 (signal transducer and activator factor) signal …

… liver transplant failure (51, 56) and treating fatty liver disease (51). The role of IL-6 in the
liver is … action of oncostatin M through the gp130 signal transducer. Embo J. 1999;18:2127-2136. …

… viral hepatitis do have additional liver diseases such as alcoholic liver disease or suboptimal
dietary … intercellular signaling. Matrix deposition finally leads to an irreversible increase of …

… but did not reverse fatty liver development. Thus the molecular … signal transducers and
activators of transcription (STAT) family members. Conclusion: Aberrant cytokine-Stat5 signaling …

… Signal transducer and activator of transcription 3 (Stat3) is the main mediator of interleukin-6–type
cytokine signaling required … and other cholestatic liver diseases remains unresolved. …

Background With the high prevalence of diffuse liver disease there is a strong clinical need
for noninvasive detection and grading of fibrosis and steatosis as well as detection of …