Regulation of liver inflammatory injury by signal transducer and activator of transcription-6
A Kato, H Yoshidome, MJ Edwards… - The American journal of …, 2000 - Elsevier
… Signal transducer and activator of transcription-6 (STAT6) is … ) of STAT6 in liver during
inflammation induced by ischemia/… in the regulation of the acute inflammatory response in liver. …
inflammation induced by ischemia/… in the regulation of the acute inflammatory response in liver. …
[HTML][HTML] Signal transducer and activator of transcription 3 in liver diseases: a novel therapeutic target
… In this review, we highlight recent advances of STAT3 signaling in liver injury, steatosis,
inflammation, regeneration, fibrosis, and hepatocarcinogenesis. The cytokines and small …
inflammation, regeneration, fibrosis, and hepatocarcinogenesis. The cytokines and small …
[HTML][HTML] Signal transducer and activator of transcription 4 in liver diseases
… documented in liver inflammatory response, liver injury and inhibition of virus replication.
Moreover, the activation of STAT4 was also detected in several models of liver injury including …
Moreover, the activation of STAT4 was also detected in several models of liver injury including …
[PDF][PDF] Inflammation‐associated interleukin‐6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in …
… promotes inflammation, whereas inflammation in … -inflammatory cytokine, exacerbates liver
inflammation, steatosis, and hepatocellular damage in alcoholic and nonalcoholic fatty liver …
inflammation, steatosis, and hepatocellular damage in alcoholic and nonalcoholic fatty liver …
Cell type–dependent pro-and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury
N Horiguchi, L Wang, P Mukhopadhyay, O Park… - Gastroenterology, 2008 - Elsevier
… In this study, we explored the functions of STAT3 in alcoholic liver … inflammation, whereas
in macrophages STAT3 activation inhibits liver inflammation during chronic alcoholic liver …
in macrophages STAT3 activation inhibits liver inflammation during chronic alcoholic liver …
[PDF][PDF] Signal transducer and activator of transcription 3 signaling within hepatocytes attenuates systemic inflammatory response and lethality in septic mice
R Sakamori, T Takehara, C Ohnishi, T Tatsumi… - …, 2007 - Wiley Online Library
… inflammatory response leading to multiorgan failure and occasionally death. During this
process, signal transducer and activator of transcription 3 (STAT3) is activated in the liver, but …
process, signal transducer and activator of transcription 3 (STAT3) is activated in the liver, but …
[PDF][PDF] Dissociation between liver inflammation and hepatocellular damage induced by carbon tetrachloride in myeloid cell–specific signal transducer and activator of …
… inflammation may attenuate liver necrosis induced by carbon tetrachloride (CCl4) in myeloid-specific
signal transducer … As an important anti-inflammatory signal, conditional deletion of …
signal transducer … As an important anti-inflammatory signal, conditional deletion of …
[HTML][HTML] Decoding cell death signals in liver inflammation
… Of note, the acute phase protein IL-6 has been recently suggested to play a prominent role
in hepatic carcinogenesis as it activates signal transducer and activator of transcription 3 (…
in hepatic carcinogenesis as it activates signal transducer and activator of transcription 3 (…
[HTML][HTML] … protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of …
A Nerstedt, A Johansson, CX Andersson, E Cansby… - Diabetologia, 2010 - Springer
… and lipid oxidation in the liver [7], also inhibits cytokine-induced inflammation in this tissue. …
point of convergence of metabolic and inflammatory signals in the liver, and may provide a …
point of convergence of metabolic and inflammatory signals in the liver, and may provide a …
[PDF][PDF] Interplay of hepatic and myeloid signal transducer and activator of transcription 3 in facilitating liver regeneration via tempering innate immunity
H Wang, O Park, F Lafdil, K Shen, N Horiguchi… - …, 2010 - Wiley Online Library
… To further understand the interaction of myeloid and hepatic STAT3 in controlling liver
inflammation and regeneration, we also generated hepatocyte-specific STAT3 knockout (…
inflammation and regeneration, we also generated hepatocyte-specific STAT3 knockout (…
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