… that is employed in this analysis, network size has limited effects … be generalized to signal
transduction networks of larger size. … relate this analysis to real signal transduction networks we …

In this article, optimization-based frameworks are introduced for elucidating the input-output
structure of signaling networks and for pinpointing targeted disruptions leading to the …

… Taken together, the simulations suggest that the topology of signal transduction networks …
In summary, these cellular changes can cause abnormal expression of proteins involved in …

… Signal transduction networks have only been studied at a small scale because large-scale …
analysis methods have not been available. Since reconstructions of large signaling networks …

… to analyze and describe such signal transduction networks in … of the topological features of
the MAPK network were found to … be considered in signal transduction networks is redundancy…

… of signal transduction networks, how those networks are … and accurate reconstruction
of network topology. Data on … EGF signalling network, we performed the same analysis on …

… of signal transduction networks due to changes in kinetic parameters and network topology.
… We analyze the effect of strong and weak interactions by simulating SNs evolution for three …

… ‐protein signal transduction circuit that mediates immediate‐early signalling downstream of
… (on and off), fitting errors would be too large to distinguish differences in pathway topology. …

… While the topological analysis of metabolic networks is a well-established field, … signal
transduction networks. Despite of a great body of information about many details of different signal …

… The pairwise disconnectivity index as a new metric for the topological analysis of
regulatory networks. BMC Bioinformatics, 9: 227 Potapov AP, Voss N, Sasse N, et al. 2005. …