Dynamic control of signaling by modular adaptor proteins

T Pawson - Current opinion in cell biology, 2007 - Elsevier
… Indeed the trafficking of signaling proteins is itself dependent on adaptor proteins, such as
… analysis of signaling adaptors and scaffold proteins. Regulation of adaptors and scaffolds by …

Signaling through scaffold, anchoring, and adaptor proteins

T Pawson, JD Scott - Science, 1997 - science.org
protein modules, adaptor molecules, targeting subunits, and anchoring proteins that coordinate
signaling … One way receptors may amplify their signaling is to use adaptor proteins that …

Vav proteins, adaptors and cell signaling

XR Bustelo - Oncogene, 2001 - nature.com
… Vav proteins may also act as adaptor … of adaptor proteins in the regulation of Vav proteins
at different levels. Given the monographic focus of this issue in the function of adaptor proteins, …

Oncogenic signaling adaptor proteins

LY Luo, WC Hahn - Journal of Genetics and Genomics, 2015 - Elsevier
Signal transduction pathways activated by receptor tyrosine kinases (RTK) play a critical …
Adaptor proteins serve an important scaffolding function that facilitates key signaling

Oncogenic transformation by the signaling adaptor proteins insulin receptor substrate (IRS)-1 and IRS-2

RK Dearth, X Cui, HJ Kim, DL Hadsell, AV Lee - Cell cycle, 2007 - Taylor & Francis
… related intracellular signaling adaptor proteins that integrate and coordinate numerous
biologically key extracellular signals within the cell.First identified as signaling intermediates of …

Adaptor proteins in protein kinase C-mediated signal transduction

D Schechtman, D Mochly-Rosen - Oncogene, 2001 - nature.com
Adaptor proteins are key to organizing signaling enzymes near their select substrates and
… role of adaptor proteins in determining the specific function of individual protein kinase C (…

APPL1 is a multifunctional endosomal signaling adaptor protein

NL Diggins, DJ Webb - Biochemical Society Transactions, 2017 - portlandpress.com
… because it can facilitate signaling pathway cross-talk on … insulin signaling pathways by
bringing together proteins involved … as an adaptor protein and how APPL1 coordinates signaling

[HTML][HTML] Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65

H Jumaa, B Wollscheid, M Mitterer, J Wienands… - Immunity, 1999 - cell.com
… During signal transduction through the B cell antigen receptor (BCR), several signaling
elements are brought together by the adaptor protein SLP-65. We have investigated the role of …

Regulation of B-cell signal transduction by adaptor proteins

T Kurosaki - Nature Reviews Immunology, 2002 - nature.com
… Hence, this review emphasizes the common ways in which a few of the crucial adaptor
proteins exert their functions, thereby tuning B-cell responses — with a particular focus on PTK …

[HTML][HTML] Crk and CrkL adaptor proteins: networks for physiological and pathological signaling

RB Birge, C Kalodimos, F Inagaki, S Tanaka - … and Signaling, 2009 - Springer
protein domains of ~100 amino acids contained within the Src oncogene and other signaling
proteins that bind tyrosine phosphorylated proteins … tyrosine phosphorylated proteins. SH3 …