[HTML][HTML] Quantitative analysis of signaling networks
HM Sauro, BN Kholodenko - Progress in biophysics and molecular biology, 2004 - Elsevier
… attempting to achieve, what is the data integration that is occurring and what parallel, if
any, can we find between natural signaling networks and man-made networks. There is a …
any, can we find between natural signaling networks and man-made networks. There is a …
[HTML][HTML] The JAK-STAT signaling network in the human B-cell: an extreme signaling pathway analysis
JA Papin, BO Palsson - Biophysical journal, 2004 - cell.com
… Herein, a reconstruction of the JAK-STAT signaling system in the human B-cell is described
… network analysis is presented. This approach is called extreme signaling pathway analysis …
… network analysis is presented. This approach is called extreme signaling pathway analysis …
A methodology for the structural and functional analysis of signaling and regulatory networks
S Klamt, J Saez-Rodriguez, JA Lindquist, L Simeoni… - BMC …, 2006 - Springer
… Here, we introduce a different approach where the circuits are identified as elementary
modes establishing a direct link to metabolic network analysis. Circuits can be formally …
modes establishing a direct link to metabolic network analysis. Circuits can be formally …
Boolean network analysis of a neurotransmitter signaling pathway
… The purpose of modeling this network between two neurotransmitter-signaling systems is
to show that a Boolean network may be used as a tool to understand the dynamics of a …
to show that a Boolean network may be used as a tool to understand the dynamics of a …
Introduction to network analysis in systems biology
A Ma'ayan - Science signaling, 2011 - science.org
… of network analysis and modeling. This advanced material is not appropriate for those with
limited experience in network analysis. … Network analysis of biological systems is increasingly …
limited experience in network analysis. … Network analysis of biological systems is increasingly …
Topological analysis of mass-balanced signaling networks: a framework to obtain network properties including crosstalk
JA Papin, BO Palsson - Journal of theoretical biology, 2004 - Elsevier
… the network structure of large-scale signaling systems. This analysis focuses on the structure
of signaling networks; future work will need to account for compartmentalization of signaling …
of signaling networks; future work will need to account for compartmentalization of signaling …
A directed protein interaction network for investigating intracellular signal transduction
A Vinayagam, U Stelzl, R Foulle, S Plassmann… - … signaling, 2011 - science.org
… 4B), suggesting that MAPK6 is linked to EGF/ERK signaling in mammalian cells. Further
network analysis revealed 151 interaction partners for MAPK6, a large fraction of which (24 …
network analysis revealed 151 interaction partners for MAPK6, a large fraction of which (24 …
Molecular signaling network complexity is correlated with cancer patient survivability
D Breitkreutz, L Hlatky, E Rietman… - Proceedings of the …, 2012 - National Acad Sciences
… signaling network, we asked if there are “signatures” embedded in these networks that
inform us as to the 5-y survival. In other words, are there statistical metrics of the network that …
inform us as to the 5-y survival. In other words, are there statistical metrics of the network that …
T cell-signaling network analysis reveals distinct differences between CD28 and CD2 costimulation responses in various subsets and in the MAPK pathway between …
ME Kalland, NG Oberprieler, T Vang… - The Journal of …, 2011 - journals.aai.org
… analysis of T cell signaling described in this report revealed time-dependent activation/inactivation
of the signaling intermediates tested. Generally, TCR-proximal signaling proteins …
of the signaling intermediates tested. Generally, TCR-proximal signaling proteins …
SignaLink 2–a signaling pathway resource with multi-layered regulatory networks
… each signaling protein is regulated. The customizable download page enables the analysis
of any user-specified part of the signaling network. Compared to other signaling resources, …
of any user-specified part of the signaling network. Compared to other signaling resources, …
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